Pseudomembranous colitis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Symptoms

Pseudomembranous colitis is characterized by

• Diarrhea: Usually, the diarrhea is non-bloody, although blood may be present if the affected individual is taking blood thinners or has an underlying lower bowel condition such as hemorrhoids.
• Abdominal pain: Abdominal pain is almost always present and may be severe. So-called "peritoneal" signs (e.g. rebound tenderness) may be present.
• Fever: "Constitutional" signs such as fever, fatigue, and loss of appetite are prominent.