Dermatomyositis differential diagnosis: Difference between revisions
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There is some overlap in the microscopic appearances of different inflammatory myopathies, but some helpful differences are often present.{{Ref|Nirmalananthan2004}} The rimmed vacuoles of [[Inclusion body myositis|inclusion body myositis]] (IBM) are absent in dermatomyositis. Polymyositis is characterised by diffuse or patchy inflammation of the muscle fascicles, a random pattern of muscle atrophy, and T-cell predominance with T-cells seen invading otherwise viable appearing muscle fibers.{{Ref|Benveniste2004}} | There is some overlap in the microscopic appearances of different inflammatory myopathies, but some helpful differences are often present.{{Ref|Nirmalananthan2004}} The rimmed vacuoles of [[Inclusion body myositis|inclusion body myositis]] (IBM) are absent in dermatomyositis. Polymyositis is characterised by diffuse or patchy inflammation of the muscle fascicles, a random pattern of muscle atrophy, and T-cell predominance with T-cells seen invading otherwise viable appearing muscle fibers.{{Ref|Benveniste2004}} | ||
Diseases that can present with similar symptoms as those of dermatomyositis are- | |||
*[[Hypothyroidism]] | |||
*[[Sarcoidosis]] | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 16:22, 30 October 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Differentiating Dermatomyositis from other Diseases
Dermatomyositis must be differentiated from other common, lymphocyte predominant inflammatory myopathies. If present, the characteristic perifascicular atrophy makes this distinction trivial.
There is some overlap in the microscopic appearances of different inflammatory myopathies, but some helpful differences are often present.[2] The rimmed vacuoles of inclusion body myositis (IBM) are absent in dermatomyositis. Polymyositis is characterised by diffuse or patchy inflammation of the muscle fascicles, a random pattern of muscle atrophy, and T-cell predominance with T-cells seen invading otherwise viable appearing muscle fibers.[3]
Diseases that can present with similar symptoms as those of dermatomyositis are-