Amyloidosis medical therapy: Difference between revisions
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==Medical Therapy== | ==Medical Therapy== | ||
Some patients with primary [[amyloidosis]] respond to [[chemotherapy]] focused on the abnormal [[plasma cell]]s. A [[stem cell transplant]] may be done, as in [[multiple myeloma]]. | |||
* The initial target in the treatment of this disorder is to correct the organ failure, as the disease is discovered at an advanced stage. | *The initial target in the treatment of this disorder is to correct the [[organ failure]], as the disease is discovered at an advanced stage. | ||
** [[Nephrotic syndrome]] is treated using supportive therapy and [[diuretics]]. | **[[Nephrotic syndrome]] is treated using supportive therapy and [[diuretics]]. | ||
** [[Renal failure]] is treated with [[dialysis]] | **[[Renal failure]] is treated with [[dialysis]]. | ||
** [[Heart failure]] is treated using [[diuretics]] | **[[Heart failure]] is treated using [[diuretics]]. | ||
** Gastrointestinal and nerve involvement are treated symptomatically. | **Gastrointestinal and nerve involvement are treated symptomatically. | ||
Treatment options with limited success include [[melphalan]], [[prednisone]], and [[colchicine]]. | |||
In secondary [[amyloidosis]], aggressively treating the disease that is causing the excess [[amyloid]] protein can improve symptoms and/or slow the disease from getting worse. Complications such as [[heart failure]], [[renal failure]], and other problems can sometimes be treated, when needed. | |||
== References == | == References == | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 14:18, 26 November 2012
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Amyloidosis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Amyloidosis medical therapy On the Web |
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American Roentgen Ray Society Images of Amyloidosis medical therapy |
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Risk calculators and risk factors for Amyloidosis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
There is no treatment for primary amyloidosis. Since the disease is typically discovered at an advanced stage, the initial treatment is aimed at stopping and correcting organ failure.
Medical Therapy
Some patients with primary amyloidosis respond to chemotherapy focused on the abnormal plasma cells. A stem cell transplant may be done, as in multiple myeloma.
- The initial target in the treatment of this disorder is to correct the organ failure, as the disease is discovered at an advanced stage.
- Nephrotic syndrome is treated using supportive therapy and diuretics.
- Renal failure is treated with dialysis.
- Heart failure is treated using diuretics.
- Gastrointestinal and nerve involvement are treated symptomatically.
Treatment options with limited success include melphalan, prednisone, and colchicine.
In secondary amyloidosis, aggressively treating the disease that is causing the excess amyloid protein can improve symptoms and/or slow the disease from getting worse. Complications such as heart failure, renal failure, and other problems can sometimes be treated, when needed.