Chronic liver disease causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Causes

Common Causes

• Cirrhosis
• Alcoholic liver disease
• Hepatitis C
• Hepatitis B
• Autoimmune hepatitis
• Portal hypertension
• Hemochromatosis
• Wilson's disease
• Gaucher disease
• Hepatoma
• Primary biliary cirrhosis
• Primary sclerosing cholangitis
• Sarcoidosis
• Zellweger syndrome

Causes by Organ System

Cardiovascular	Right heart failure
Chemical / poisoning	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	Methotrexate, Nitrofurantoin
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	Autoimmune hepatitis, Cirrhosis, Hepatitis B , Hepatitis C, Hepatoma, Non-alcoholic fatty liver disease, Portal hypertension, Primary biliary cirrhosis , Primary sclerosing cholangitis, Sarcoidosis, Wilson's disease
Genetic	Gaucher disease, Hemochromatosis, Sarcoidosis, Wilson's disease, Zellweger syndrome
Hematologic	No underlying causes
Iatrogenic	No underlying causes
Infectious Disease	Cytomegalovirus (CMV), Epstein Barr virus (EBV), Hepatitis B , Hepatitis C
Musculoskeletal / Ortho	No underlying causes
Neurologic	Wilson's disease
Nutritional / Metabolic	Gaucher disease, Hemochromatosis, Zellweger syndrome
Obstetric/Gynecologic	No underlying causes
Oncologic	Hepatoma
Opthalmologic	Wilson's disease
Overdose / Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	Sarcoidosis
Renal / Electrolyte	No underlying causes
Rheum / Immune / Allergy	Autoimmune hepatitis, Primary biliary cirrhosis , Primary sclerosing cholangitis, Sarcoidosis
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Dental	No underlying causes
Miscellaneous	Alcoholic liver disease

Causes in Alphabetical Order

• Alcoholic liver disease
• Autoimmune hepatitis
• Cirrhosis
• Cytomegalovirus (CMV)
• Epstein Barr virus (EBV)
• Gaucher disease
• Hemochromatosis
• Hepatitis B
• Hepatitis C
• Hepatoma
• Metabolic
• Methotrexate
• Nitrofurantoin
• Non-alcoholic fatty liver disease
• Portal hypertension
• Primary biliary cirrhosis
• Primary sclerosing cholangitis
• Right heart failure
• Sarcoidosis
• Wilson's disease
• Zellweger syndrome