Amyloidosis other imaging findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Tissue Doppler echocardiography and myocardial strain rate imaging has been shown to be very sensitive for the assessment of myocardial dysfunction in restrictive cardiomyopathy. The developmend of Serum amyloid P component (SAP) scans has given physicians the ability to specifically locate amyloid deposits.

Other Imaging Findings

• In addition, all amyloid deposits contain serum amyloid P component (SAP), a circulating protein of the pentraxin family. Radionuclide SAP scans have been developed which can anatomically localize amyloid deposits in patients.
• Tissue Doppler and myocardial strain rate imaging has been proven to be very sensitive for the assessment of myocardial dysfunction in restrictive cardiomyopathy. Doppler studies may show abnormal wall motion early in the disease process.
• Abdominal ultrasound may reveal a swollen liver or spleen.