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| {{Lymphogranuloma venereum}} | | {{Lymphogranuloma venereum}} |
| {{CMG}}
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| ==Overview==
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| ==Physical Examination==
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| ===Primary stage===
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| LGV may begin as a self-limited painless genital [[ulcer]] that occurs at the contact site 3-12 days '''or longer''' in this primary stage. Rarely do women notice a primary infection, because the initial ulceration where the organism penetrates the mucosal layer are located out of sight in the vaginal wall. Also in men fewer than 1/3 of those infected notice the first signs of LGV. This primary stage heals in a few days. [[Erythema nodosum]] occurs in 10% of cases.
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| ===Secondary stage===
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| The secondary stage occurs from 10-30 days later most often, but has occurred up to 6 months later. The infection is then spread to the lymph nodes through [[lymphatic drainage]] pathways. The most frequent presenting clinical manifestation of LGV among males whose primary exposure was genital is unilateral, in 2/3 of cases, [[adenitis|lymphadenitis]] and [[lymphangitis]], often tender inguinal and/or femoral lymphadenopathy because of the drainage pathway for their likely infected areas. Lymphangitis of the dorsal penis may also occur and resembles string or cord. If the route was anal sex the infected person may experience lymphadenitis and lymphangitis noted above or may have proctitis, inflammation limited to the rectum (the distal 10--12 cm) that may be associated with anorectal pain, [[tenesmus]], or rectal discharge, or [[proctocolitis]], inflammation of the colonic [[mucosa]] extending to 12 cm above the anus and is associated with symptoms of [[proctitis]] plus diarrhea or abdominal cramps and or inflammatory involvement of perirectal or perianal [[lymphatic tissue]]s. In females [[cervicitis]], perimetritis, or [[salpingitis]] may occur as well as the [[lymphangitis]] and [[lymphadenitis]] in deeper nodes. Because of lymphatic drainage pathways, some end up with an abdominal mass which seldom suppurates and only 20-30% end up with inguinal lymphadenopathy. Systemic signs: fever, decreased appetite, and malaise, may occur as well. Diagnosis is more difficult in women and homosexual men who may not have the inguinal symptoms.
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| Over the course of the disease, lymph nodes enlarge, enlarged nodes are called buboes, and become painful at first (which may occur in any infection of the same areas as well). The next most common thing is inflammation, thinning and fixation of the overlying skin. Lastly in the progression are [[necrosis]], fluctuant and suppurative lymph nodes, [[abscess]]es, fistulas, strictures, and sinus tracts all may occur. During the infection and when it subsides and healing takes place, fibrosis may occur. This can result in varying degrees of lymphatic obstruction, chronic [[edema]], and [[stricture]]s. These late stages characterised by fibrosis and edema are also known as the third stage of LGV and are mainly permanent.
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| ==References== | | ==References== |
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| [[Category:Sexually transmitted diseases]] | | [[Category:Sexually transmitted diseases]] |
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| [[Category:Disease]] | | [[Category:Disease]] |
| [[Category:Gynecology]] | | [[Category:Gynecology]] |
| [[Category:Infectious disease]] | | [[Category:Infectious disease]] |
| [[Category:Needs overview]] | | [[Category:Needs content]] |
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| {{WikiDoc Help Menu}} | | {{WikiDoc Help Menu}} |
| {{WikiDoc Sources}} | | {{WikiDoc Sources}} |