Inflammatory bowel disease classification: Difference between revisions
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The main difference between Crohn's disease and UC is the location and nature of the inflammatory changes. Crohn's can affect any part of the [[gastrointestinal tract]], from [[mouth]] to [[anus]] (skip lesions), although a majority of the cases start in the [[terminal ileum|terminal]] [[ileum]]. Ulcerative colitis, in contrast, is restricted to the [[colon (anatomy)|colon]] and the anus. | The main difference between Crohn's disease and UC is the location and nature of the inflammatory changes. Crohn's can affect any part of the [[gastrointestinal tract]], from [[mouth]] to [[anus]] (skip lesions), although a majority of the cases start in the [[terminal ileum|terminal]] [[ileum]]. Ulcerative colitis, in contrast, is restricted to the [[colon (anatomy)|colon]] and the anus. <ref>http://www.ccfa.org</ref> | ||
[[Light microscopy|Microscopically]], ulcerative colitis is restricted to the [[mucosa]] ([[epithelium|epithelial lining]] of the gut), while Crohn's disease affects the whole bowel wall. | [[Light microscopy|Microscopically]], ulcerative colitis is restricted to the [[mucosa]] ([[epithelium|epithelial lining]] of the gut), while Crohn's disease affects the whole bowel wall. | ||
Revision as of 17:59, 21 March 2013
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Inflammatory Bowel Disease Main page |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Classification
The main forms of IBD are Crohn's disease and ulcerative colitis (UC).
Accounting for far fewer cases are other forms of IBD:
- Collagenous colitis
- Lymphocytic colitis
- Ischaemic colitis
- Diversion colitis
- Behçet's syndrome
- Infective colitis
- Indeterminate colitis
The main difference between Crohn's disease and UC is the location and nature of the inflammatory changes. Crohn's can affect any part of the gastrointestinal tract, from mouth to anus (skip lesions), although a majority of the cases start in the terminal ileum. Ulcerative colitis, in contrast, is restricted to the colon and the anus. [1]
Microscopically, ulcerative colitis is restricted to the mucosa (epithelial lining of the gut), while Crohn's disease affects the whole bowel wall.
Finally, Crohn's disease and ulcerative colitis present with extra-intestinal manifestations (such as liver problems, arthritis, skin manifestations and eye problems) in different proportions.
In rare cases, patients have been diagnosed with both Crohn's disease and ulcerative colitis, which is really called Crohn's colitis.