Hepatitis D other diagnostic studies: Difference between revisions
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===Liver Biopsy:=== | ===Liver Biopsy:=== | ||
Liver transplant is the only remaining treatment option for patients with liver failure who are not candidates for treatment with interferon-alpha. | |||
*Liver biopsy is not routinely indicated in diagnosis of acute hepatitis D unless the serologic diagnosis of hepatitis is inconclusive. However, liver biopsy is indicated in chronic liver disease to evaluate for [[cirrhosis]] or [[fibrosis]]. | *Liver biopsy is not routinely indicated in diagnosis of acute hepatitis D unless the serologic diagnosis of hepatitis is inconclusive. However, liver biopsy is indicated in chronic liver disease to evaluate for [[cirrhosis]] or [[fibrosis]]. | ||
Revision as of 11:11, 7 August 2014
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Hepatitis D |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S. [2]
Other Diagnostic Studies
Liver Biopsy:
Liver transplant is the only remaining treatment option for patients with liver failure who are not candidates for treatment with interferon-alpha.
- Liver biopsy is not routinely indicated in diagnosis of acute hepatitis D unless the serologic diagnosis of hepatitis is inconclusive. However, liver biopsy is indicated in chronic liver disease to evaluate for cirrhosis or fibrosis.
- Histopathologic findings are similar to that observed in HBV infection. Acidophilic cytoplasm in hepatocytes with lymphocytic infiltrates may be observed.
- Immunohistochemical staining may be positive for HDV antigen with suppression of HBsAg in case of superinfection.