Cyclosporiasis pathophysiology: Difference between revisions
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[[Image:Cyclosporiasis.gif|right|thumbnail|Life cycle of Cyclosporiasis]] | |||
{{Cyclosporiasis}} | {{Cyclosporiasis}} | ||
{{CMG}} | {{CMG}} | ||
==Pathophysiology== | ==Pathophysiology== | ||
When freshly passed in stools, the oocyst is not infective (thus, direct fecal-oral transmission cannot occur; this differentiates Cyclospora from another important coccidian parasite, Cryptosporidium). In the environment, sporulation occurs after days or weeks at temperatures between 22°C to 32°C, resulting in division of the sporont into two sporocysts, each containing two elongate sporozoites. Fresh produce and water can serve as vehicles for transmission and the sporulated oocysts are ingested (in contaminated food or water). The oocysts excyst in the gastrointestinal tract, freeing the sporozoites which invade the epithelial cells of the small intestine. Inside the cells they undergo asexual multiplication and sexual development to mature into oocysts, which will be shed in stools. The potential mechanisms of contamination of food and water are still under investigation. | |||
When freshly passed in stools, the oocyst is not infective | |||
==References == | ==References == | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 21:25, 22 July 2013
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Cyclosporiasis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Cyclosporiasis pathophysiology On the Web |
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American Roentgen Ray Society Images of Cyclosporiasis pathophysiology |
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Risk calculators and risk factors for Cyclosporiasis pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Pathophysiology
When freshly passed in stools, the oocyst is not infective (thus, direct fecal-oral transmission cannot occur; this differentiates Cyclospora from another important coccidian parasite, Cryptosporidium). In the environment, sporulation occurs after days or weeks at temperatures between 22°C to 32°C, resulting in division of the sporont into two sporocysts, each containing two elongate sporozoites. Fresh produce and water can serve as vehicles for transmission and the sporulated oocysts are ingested (in contaminated food or water). The oocysts excyst in the gastrointestinal tract, freeing the sporozoites which invade the epithelial cells of the small intestine. Inside the cells they undergo asexual multiplication and sexual development to mature into oocysts, which will be shed in stools. The potential mechanisms of contamination of food and water are still under investigation.