Coccidioidomycosis historical perspective: Difference between revisions
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==Historical Perspective== | ==Historical Perspective== | ||
*In 1892, Alejandro Posadas (a medical student) along with his mentor, Robert Wernicke discovered coccidomycosis . | |||
*In 1896, Emmet Rixford and T. Caspar Gilchrist coined the term coccidomycosis (resembling Coccidia), they also grouped coccidomycosis under parasitic family. | |||
*In 1900, William Ophüls and Herbert C. Moffitt described its dimorphic nature and defined it as a fungal etiology. | |||
*In 1914, Cooke discovered coccidioidin skin test using precipitin reaction for the first time in diagnosing coccidomycosis. | |||
===Biological Warfare=== | ===Biological Warfare=== | ||
''C. immitis'' was investigated by the United States during the 1950s and 1960s as a potential biological weapon. The Cash strain received the military symbol OC, and original hopes were for its use as an incapacitant. As medical epidemiology later made clear, OC would have lethal effects on several segments of the population, so it was later considered a lethal agent. It was never standardized, | ''C. immitis'' was investigated by the United States during the 1950s and 1960s as a potential biological weapon. The Cash strain received the military symbol OC, and original hopes were for its use as an incapacitant. As medical epidemiology later made clear, OC would have lethal effects on several segments of the population, so it was later considered a lethal agent. It was never standardized, around beyond a few field trials, it was never weaponized. Most military work on OC was on vaccines by the mid-1960s. | ||
==References== | ==References== | ||
Revision as of 17:24, 8 March 2017
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Coccidioidomycosis Microchapters |
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Coccidioidomycosis historical perspective On the Web |
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Risk calculators and risk factors for Coccidioidomycosis historical perspective |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Historical Perspective
- In 1892, Alejandro Posadas (a medical student) along with his mentor, Robert Wernicke discovered coccidomycosis .
- In 1896, Emmet Rixford and T. Caspar Gilchrist coined the term coccidomycosis (resembling Coccidia), they also grouped coccidomycosis under parasitic family.
- In 1900, William Ophüls and Herbert C. Moffitt described its dimorphic nature and defined it as a fungal etiology.
- In 1914, Cooke discovered coccidioidin skin test using precipitin reaction for the first time in diagnosing coccidomycosis.
Biological Warfare
C. immitis was investigated by the United States during the 1950s and 1960s as a potential biological weapon. The Cash strain received the military symbol OC, and original hopes were for its use as an incapacitant. As medical epidemiology later made clear, OC would have lethal effects on several segments of the population, so it was later considered a lethal agent. It was never standardized, around beyond a few field trials, it was never weaponized. Most military work on OC was on vaccines by the mid-1960s.