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==Classification==
==Classification==
There are four distinct clinical syndromes:
There are four distinct clinical syndromes:
* Infection in pregnancy: ''Listeria'' can proliferate asymptomatically in the vagina and uterus. If the mother becomes symptomatic, it is usually in the third trimester. Symptoms include [[fever]], [[myalgia]]s, [[arthralgias]] and [[headache]]. Abortion, stillbirth and preterm labor are complications of GU infection.
 
* Neonatal infection (granulomatosis infantisepticum): There are two forms. One, an early-onset [[sepsis]], with ''Listeria'' acquired in utero, results in premature birth. ''Listeria'' can be isolated in the [[placenta]], [[blood]], [[meconium]], [[nose]], [[ear]]s, and [[throat]]. Another, late-onset meningitis is acquired through vaginal transmission, although it also has been reported with caesarean deliveries.
* '''Infection in pregnancy''': ''Listeria'' can proliferate asymptomatically in the [[vagina]] and [[uterus]]. If the mother becomes symptomatic, it is usually in the third [[trimester]]. Symptoms include [[fever]], [[myalgia]]s, [[arthralgias]] and [[headache]]. [[Abortion]], [[stillbirth]], and [[preterm labor]] are complications of genitourinary infection.
* [[Central nervous system|CNS]] infection: ''Listeria'' has a predilection for the brain [[parenchyma]], especially the [[brain stem]], and the [[meninges]]. Mental status changes are common. Seizures occur in at least 25% of patients. Cranial nerve palsies, [[encephalitis]], [[meningitis]], [[meningoencephalitis]] and [[abscess]]es can all occur.
 
* [[Gastroenteritis]]: ''L monocytogenes'' can produce food-borne diarrheal disease, which typically is noninvasive. The median incubation period is 1-2 days, with diarrhea lasting anywhere from 1-3 days. Patients present with fever, muscle aches, gastrointestinal nausea or diarrhea, headache, stiff neck, confusion, loss of balance, or convulsions.
* '''Neonatal infection''' ('''granulomatosis infantisepticum'''): There are two forms. One, an early-onset [[sepsis]], with ''Listeria'' acquired in utero, results in premature birth. ''Listeria'' can be isolated in the [[placenta]], [[blood]], [[meconium]], [[nose]], [[ear]]s, and [[throat]]. Another, late-onset [[meningitis]] is acquired through vaginal transmission, although it also has been reported with caesarean deliveries.
 
* '''CNS infection''': ''Listeria'' has a predilection for the brain [[parenchyma]], especially the [[brain stem]], and the [[meninges]]. Mental status changes are common. [[Seizure]]s occur in at least 25% of patients. Cranial nerve palsies, [[encephalitis]], [[meningitis]], [[meningoencephalitis]], or [[abscess]]es may occur.
 
* '''Gastroenteritis''': ''Listeria monocytogenes'' can produce food-borne diarrheal disease, which typically is noninvasive. The median incubation period is 1-2 days, with [[diarrhea]] lasting anywhere from 1-3 days. Patients present with [[fever]], [[muscle ache]]s, [[nausea]], [[diarrhea]], [[headache]], [[stiff neck]], [[confusion]], loss of balance, or [[convulsion]]s.


==References==
==References==
{{reflist|2}}
{{reflist|2}}
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[[Category:Bacterial diseases]]
[[Category:Bacterial diseases]]
[[Category:Disease]]
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[[Category:Infectious disease]]
[[Category:Needs overview]]
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Revision as of 20:51, 23 February 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Classification

There are four distinct clinical syndromes:

  • Neonatal infection (granulomatosis infantisepticum): There are two forms. One, an early-onset sepsis, with Listeria acquired in utero, results in premature birth. Listeria can be isolated in the placenta, blood, meconium, nose, ears, and throat. Another, late-onset meningitis is acquired through vaginal transmission, although it also has been reported with caesarean deliveries.

References