Toxoplasmosis medical therapy: Difference between revisions
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==Medical Therapy== | ==Medical Therapy== | ||
Teatment is not needed for a healthy person who is not pregnant. Symptoms will usually go away within a few weeks. Treatment may be recommended for pregnant women or persons who have weakened immune systems <ref>http://www.dpd.cdc.gov/dpdx/HTML/Toxoplasmosis.htm</ref>. | |||
=== Pharmacotherapy === | |||
Medications that are prescribed for acute Toxoplasmosis are: | |||
* [[Pyrimethamine]] — an [[antimalarial medication]]. | |||
* [[Sulfadiazine]] — an [[antibiotic]] used in combination with pyrimethamine to treat toxoplasmosis. | |||
* [[clindamycin]] — an antibiotic. This is used most often for people with HIV/AIDS. | |||
* [[spiramycin]] — another antibiotic. This is used most often for pregnant women to prevent the infection of their child. | |||
(Other antibiotics such as [[minocycline]] have seen some use as a salvage therapy). | |||
Medications that are prescribed for latent Toxoplasmosis are: | |||
* [[atovaquone]] — an antibiotic that has been used to kill Toxoplasma cysts in situ in [[AIDS]] patients. <ref> | |||
{{cite web | title=Toxoplasmosis - treatment key research | url=http://www.aidsmap.com/en/docs/659BAD5D-332A-4F8D-9F93-8D0F470B2D32.asp | date=2005-11-02 | publisher=NAM & aidsmap}}</ref> | |||
* [[clindamycin]] — an antibiotic which, in combination with atovaquone, seemed to optimally kill cysts in mice.<ref> | |||
{{cite journal | author = Djurković-Djaković O, Milenković V, Nikolić A, Bobić B, Grujić J | title = Efficacy of atovaquone combined with clindamycin against murine infection with a cystogenic (Me49) strain of Toxoplasma gondii. | journal = J Antimicrob Chemother | volume = 50 | issue = 6 | pages = 981-7 | year = 2002 | id = PMID 12461021 | doi = 10.1093/jac/dkf251 | url=http://jac.oxfordjournals.org/cgi/reprint/50/6/981.pdf | format=PDF}}</ref> | |||
However, in latent infections successful treatment is not guaranteed, and some subspecies exhibit resistance. | |||
==References== | ==References== | ||
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Medical Therapy
Teatment is not needed for a healthy person who is not pregnant. Symptoms will usually go away within a few weeks. Treatment may be recommended for pregnant women or persons who have weakened immune systems [1].
Pharmacotherapy
Medications that are prescribed for acute Toxoplasmosis are:
- Pyrimethamine — an antimalarial medication.
- Sulfadiazine — an antibiotic used in combination with pyrimethamine to treat toxoplasmosis.
- clindamycin — an antibiotic. This is used most often for people with HIV/AIDS.
- spiramycin — another antibiotic. This is used most often for pregnant women to prevent the infection of their child.
(Other antibiotics such as minocycline have seen some use as a salvage therapy).
Medications that are prescribed for latent Toxoplasmosis are:
- atovaquone — an antibiotic that has been used to kill Toxoplasma cysts in situ in AIDS patients. [2]
- clindamycin — an antibiotic which, in combination with atovaquone, seemed to optimally kill cysts in mice.[3]
However, in latent infections successful treatment is not guaranteed, and some subspecies exhibit resistance.
References
- ↑ http://www.dpd.cdc.gov/dpdx/HTML/Toxoplasmosis.htm
- ↑ "Toxoplasmosis - treatment key research". NAM & aidsmap. 2005-11-02.
- ↑ Djurković-Djaković O, Milenković V, Nikolić A, Bobić B, Grujić J (2002). "Efficacy of atovaquone combined with clindamycin against murine infection with a cystogenic (Me49) strain of Toxoplasma gondii" (PDF). J Antimicrob Chemother. 50 (6): 981–7. doi:10.1093/jac/dkf251. PMID 12461021.