Zygomycosis risk factors: Difference between revisions
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==Overview== | ==Overview== | ||
While most individuals are exposed to the fungi on a regular basis those with immune disorders are more prone to an infection.<ref name=medplus>{{cite web |url=http://www.nlm.nih.gov/medlineplus/ency/article/000649.htm |title=MedlinePlus Medical Encyclopedia: Mucormycosis |format= |work= |accessdate=2008-04-21}}</ref> In humans zygomycosis is most prevalent in immunocompromised patients ([[AIDS|HIV/AIDS]], the [[old age|elderly]], [[Severe combined immunodeficiency|SCID]], etc) and patients in [[acidosis]] ([[diabetes]], burns), particularly after barrier injury to the skin or [[mucus membrane]]s, malignancies such as [[lymphoma]]s and [[leukemia]]s, [[renal failure]], [[organ transplant]], long term [[corticosteroid]] and immunosuppressive therapy, [[cirrhosis]], [[burns]] and energy [[malnutrition]]. Some 50-75% of patients diagnosed with zygomycosis are estimated to have underlying poorly controlled [[diabetes mellitus]] and [[ketoacidosis]]. | While most individuals are exposed to the fungi on a regular basis those with immune disorders are more prone to an infection.<ref name=medplus>{{cite web |url=http://www.nlm.nih.gov/medlineplus/ency/article/000649.htm |title=MedlinePlus Medical Encyclopedia: Mucormycosis |format= |work= |accessdate=2008-04-21}}</ref> In humans zygomycosis is most prevalent in immunocompromised patients ([[AIDS|HIV/AIDS]], the [[old age|elderly]], [[Severe combined immunodeficiency|SCID]], etc) and patients in [[acidosis]] ([[diabetes]], burns), particularly after barrier injury to the skin or [[mucus membrane]]s, malignancies such as [[lymphoma]]s and [[leukemia]]s, [[renal failure]], [[organ transplant]], long term [[corticosteroid]] and immunosuppressive therapy, [[cirrhosis]], [[burns]] and energy [[malnutrition]]. Some 50-75% of patients diagnosed with zygomycosis are estimated to have underlying poorly controlled [[diabetes mellitus]] and [[ketoacidosis]]. | ||
==Risk factors== | |||
Mucormycosis is a rare infection caused by fungi typically found in the soil and in decaying organic matter, including leaves and rotten wood. The infection is more common among people with weakened immune systems, but it can occur (rarely) in people who are otherwise healthy. Risk factors for developing mucormycosis include: | |||
* Uncontrolled [[diabetes]] | |||
* [[Cancer]] | |||
* [[Organ transplant]] | |||
* [[Neutropenia]] (low white blood cells) | |||
* Skin [[trauma]] (cuts, scrapes, punctures, or burns) | |||
==References== | ==References== | ||
Revision as of 21:06, 22 November 2013
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Overview
While most individuals are exposed to the fungi on a regular basis those with immune disorders are more prone to an infection.[1] In humans zygomycosis is most prevalent in immunocompromised patients (HIV/AIDS, the elderly, SCID, etc) and patients in acidosis (diabetes, burns), particularly after barrier injury to the skin or mucus membranes, malignancies such as lymphomas and leukemias, renal failure, organ transplant, long term corticosteroid and immunosuppressive therapy, cirrhosis, burns and energy malnutrition. Some 50-75% of patients diagnosed with zygomycosis are estimated to have underlying poorly controlled diabetes mellitus and ketoacidosis.
Risk factors
Mucormycosis is a rare infection caused by fungi typically found in the soil and in decaying organic matter, including leaves and rotten wood. The infection is more common among people with weakened immune systems, but it can occur (rarely) in people who are otherwise healthy. Risk factors for developing mucormycosis include:
- Uncontrolled diabetes
- Cancer
- Organ transplant
- Neutropenia (low white blood cells)
- Skin trauma (cuts, scrapes, punctures, or burns)
References
- ↑ "MedlinePlus Medical Encyclopedia: Mucormycosis". Retrieved 2008-04-21.