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| * [[Convulsion|Convulsions]] | | * [[Convulsion|Convulsions]] |
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| ===Carrion's Disease===
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| The clinical symptoms of Carrion's disease are pleomorphic and some patients from endemic areas may be asymptomatic.
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| The two classical clinical presentations are the acute phase and the chronic phase, corresponding to the two different host cell types invaded by the bacterium (red blood cells and endothelial cells).
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| * Acute phase: (Carrion's disease) the most common findings are [[fever]] (usually sustained, but with temperature no greater than 102°F (39°C)), [[malaise]]. This phase is characterized by severe hemolytic anemia and transient immunosuppression. The case fatality ratios of untreated patients exceeded 40% but reach around 90% when opportunistic infection with Salmonella species occurs. In a recent study the attack rate was 13.8% (123 cases) and the case-fatality rate was 0.7%.
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| * Chronic phase: (Verruga Peruana or Peruvian Wart) it is characterized by an eruptive phase, in which the patients develop a cutaneous rash produced by a proliferation of endothelial cells and is known as "Peruvian warts" or "verruga peruana".
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| The most common findings are bleeding of verrugas, fever, [[malaise]], [[arthralgias]], [[anorexia]], [[myalgias]].
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| ===Peliosis Hepatis===
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| The condition is typically asymptomatic and is discovered following evaluation of abnormal [[liver function test]]. However, when severe it can manifest as [[jaundice]], [[hepatomegaly]], [[liver failure]] and [[Hemoperitoneum|haemoperitoneum]].
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| ===Trench Fever===
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| The disease is classically a five-day [[fever]] of the relapsing type, rarely with a continuous course instead. [[Latent period]] is relatively long (about two weeks). The onset of symptoms is usually sudden with [[high fever]], severe [[headache]], [[pain]] on moving the eyeballs, soreness of the muscles of the legs and back, and frequently [[hyperaesthesia]] of the shins. The initial fever is usually followed in a few days by a single short rise but there may be many relapses between periods without fever. The most constant symptom is pain in the legs. Recovery takes a month or more. Lethal cases are rare, but in a few cases "the persistent fever might lead to heart failure". After effects may include neurasthenia, cardiac disturbances and myalgia.
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| ==References== | | ==References== |