Syphilis management of sexual partners: Difference between revisions

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*Although such manifestations are uncommon after the first year of infection, persons exposed sexually to a patient who has syphilis in any stage should be evaluated [[Syphilis physical examination|clinically]] and [[Syphilis laboratory findings#Serology|serologically]] and treated with a recommended regimen, according to the following recommendations:
*Although such manifestations are uncommon after the first year of infection, persons exposed sexually to a patient who has syphilis in any stage should be evaluated [[Syphilis physical examination|clinically]] and [[Syphilis laboratory findings#Serology|serologically]] and treated with a recommended regimen, according to the following recommendations:


:*Persons who were exposed within the 90 days preceding the diagnosis of [[Syphilis pathophysiology#Primary syphilis|primary]], [[Syphilis pathophysiology#Secondary syphilis|secondary]], or [[Syphilis pathophysiology#Latent syphilis|early latent syphilis]] in a sex partner might be infected even if [[Syphilis laboratory tests#Serology|seronegative]]; therefore, such persons should be [[Syphilis medical therapy#Pharmacotherapy|treated presumptively]].
:*Persons who were exposed within the 90 days preceding the diagnosis of [[Syphilis pathophysiology#Primary syphilis|primary]], [[Syphilis pathophysiology#Secondary syphilis|secondary]], or [[Syphilis pathophysiology#Latent syphilis|early latent syphilis]] in a sex partner might be infected even if [[Syphilis laboratory findings#Serology|seronegative]]; therefore, such persons should be [[Syphilis medical therapy#Pharmacotherapy|treated presumptively]].


:*Persons who were exposed more than 90 days before the diagnosis of [[Syphilis pathophysiology#Primary syphilis|primary]], [[Syphilis pathophysiology#Secondary syphilis|secondary]], or [[Syphilis pathophysiology#Latent syphilis|early latent syphilis]] in a sex partner should be [[Syphilis medical therapy#Pharmacotherapy|treated presumptively]] if [[Syphilis laboratory tests#Serology|serologic test]] results are not available immediately and the opportunity for follow-up is uncertain.
:*Persons who were exposed more than 90 days before the diagnosis of [[Syphilis pathophysiology#Primary syphilis|primary]], [[Syphilis pathophysiology#Secondary syphilis|secondary]], or [[Syphilis pathophysiology#Latent syphilis|early latent syphilis]] in a sex partner should be [[Syphilis medical therapy#Pharmacotherapy|treated presumptively]] if [[Syphilis laboratory tests#Serology|serologic test]] results are not available immediately and the opportunity for follow-up is uncertain.


:*For purposes of partner notification and [[Syphilis medical therapy#Pharmacotherapy|presumptive treatment]] of exposed sex partners, patients with syphilis of unknown duration who have [[Syphilis laboratory tests#Nontreponemal test|high nontreponemal serologic test titers]] (i.e., greater than 1:32) can be assumed to have [[Syphilis pathophysiology#Primary syphilis|early syphilis]]. For the purpose of determining a treatment regimen, however, [[Syphilis laboratory tests#Serology|serologic titers]] should not be used to differentiate early from [[Syphilis pathophysiology#Latent syphilis|late latent syphilis]].
:*For purposes of partner notification and [[Syphilis medical therapy#Pharmacotherapy|presumptive treatment]] of exposed sex partners, patients with syphilis of unknown duration who have [[Syphilis laboratory findings#Nontreponemal test|high nontreponemal serologic test titers]] (i.e., greater than 1:32) can be assumed to have [[Syphilis pathophysiology#Primary syphilis|early syphilis]]. For the purpose of determining a treatment regimen, however, [[Syphilis laboratory findings#Serology|serologic titers]] should not be used to differentiate early from [[Syphilis pathophysiology#Latent syphilis|late latent syphilis]].


:*Long-term sex partners of patients who have [[Syphilis pathophysiology#Latent syphilis|latent syphilis]] should be evaluated [[Syphilis physical examination|clinically]] and [[Syphilis laboratory tests#Serology|serologically]] for syphilis and treated on the basis of the evaluation findings.
:*Long-term sex partners of patients who have [[Syphilis pathophysiology#Latent syphilis|latent syphilis]] should be evaluated [[Syphilis physical examination|clinically]] and [[Syphilis laboratory findings#Serology|serologically]] for syphilis and treated on the basis of the evaluation findings.


*Sexual partners of infected patients should be considered at risk and provided [[Syphilis medical therapy#Pharmacotherapy|treatment]] if they have had sexual contact with the patient within:
*Sexual partners of infected patients should be considered at risk and provided [[Syphilis medical therapy#Pharmacotherapy|treatment]] if they have had sexual contact with the patient within:

Revision as of 16:33, 19 December 2012

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Management of Sexual Partners

  • Sexual transmission of treponema pallidum is thought to occur only when mucocutaneous syphilitic lesions are present.
  • Although such manifestations are uncommon after the first year of infection, persons exposed sexually to a patient who has syphilis in any stage should be evaluated clinically and serologically and treated with a recommended regimen, according to the following recommendations:
  • Sexual partners of infected patients should be considered at risk and provided treatment if they have had sexual contact with the patient within:

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