Bacterial vaginosis medical therapy: Difference between revisions
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In a [[randomized controlled trial]],<ref name="pmid11127100">{{cite journal |author=Hanson JM, McGregor JA, Hillier SL, ''et al'' |title=Metronidazole for bacterial vaginosis. A comparison of vaginal gel vs. oral therapy |journal=J Reprod Med |volume=45 |issue=11 |pages=889–96 |year=2000 |pmid=11127100 |doi=}}</ref> researchers found the efficacy of 0.75% metronidazole vaginal gel in treating bacterial vaginosis (cure rate 70.7%) was equivalent to that of standard oral metronidazole treatment (cure rate 71%). Treatment with vaginal metronidazole gel was associated with fewer gastrointestinal complaints. | In a [[randomized controlled trial]],<ref name="pmid11127100">{{cite journal |author=Hanson JM, McGregor JA, Hillier SL, ''et al'' |title=Metronidazole for bacterial vaginosis. A comparison of vaginal gel vs. oral therapy |journal=J Reprod Med |volume=45 |issue=11 |pages=889–96 |year=2000 |pmid=11127100 |doi=}}</ref> researchers found the efficacy of 0.75% metronidazole vaginal gel in treating bacterial vaginosis (cure rate 70.7%) was equivalent to that of standard oral metronidazole treatment (cure rate 71%). Treatment with vaginal metronidazole gel was associated with fewer gastrointestinal complaints. | ||
{| class="wikitable" border="1" style="background:FloralWhite" | |||
|- align="center" | |||
|'''Characteristics of the Patient''' | |||
|'''Possible Pathogens''' | |||
|'''Preferred Treatment''' | |||
|'''Duration of Treatment''' | |||
|'''Alternative Treatment''' | |||
|- align="center" | |||
|'''All symptomatic women''' | |||
'''High risk asymptomatic pregnant women''' | |||
|Prevotella spp, | |||
Mobiluncus spp, | |||
G. vaginalis, | |||
Ureaplasma, | |||
Mycoplasma | |||
|'''Metronidazole gel''' | |||
0.75%, one full applicator (5 g) intravaginally, once daily | |||
|5 days | |||
|'''Metronidazole''' 500 mg PO BID for 7 days | |||
'''OR''' | |||
'''Clindamycin''' 300 mg PO BID for 7 days | |||
|} | |||
==References== | ==References== | ||
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{{WS}} | {{WS}} | ||
[[Category:Infectious disease]] | [[Category:Infectious disease]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Gynecology]] | [[Category:Gynecology]] | ||
Revision as of 18:37, 19 December 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Bacterial vaginosis Microchapters |
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Diagnosis |
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Treatment |
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Bacterial vaginosis medical therapy On the Web |
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American Roentgen Ray Society Images of Bacterial vaginosis medical therapy |
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Risk calculators and risk factors for Bacterial vaginosis medical therapy |
Overview
Treatment with appropriate antibiotics is recommended in all symptomatic women and high risk asymptomatic pregnant women.
Medical Therapy
Pharmacotherapy
Bacterial vaginosis can be treated with antibiotics such as metronidazole and clindamycin. However, there is a high rate of recurrence.
Currently, there are very few over the counter products that address bacterial vaginosis. A vaginal gel product called RepHresh claims to regulate the pH level. Boric acid capsules inserted vaginally is considered a home treatment. Lactobacillus supplements may also be used; Fem-dophilus (Jarrow Formulas) is a lactobacillus product which specifically claims to help maintain healthy vaginal flora.[1]
It should be noted that seeking medical attention is often necessary, because none of the over the counter products can claim to treat an active infection. More importantly, patients often inaccurately diagnose BV as a yeast infection, and delay proper treatment which may lead to complications.
In a randomized controlled trial,[2] researchers found the efficacy of 0.75% metronidazole vaginal gel in treating bacterial vaginosis (cure rate 70.7%) was equivalent to that of standard oral metronidazole treatment (cure rate 71%). Treatment with vaginal metronidazole gel was associated with fewer gastrointestinal complaints.
| Characteristics of the Patient | Possible Pathogens | Preferred Treatment | Duration of Treatment | Alternative Treatment |
| All symptomatic women
High risk asymptomatic pregnant women |
Prevotella spp,
Mobiluncus spp, G. vaginalis, Ureaplasma, Mycoplasma |
Metronidazole gel
0.75%, one full applicator (5 g) intravaginally, once daily
|
5 days | Metronidazole 500 mg PO BID for 7 days
OR Clindamycin 300 mg PO BID for 7 days |
References
- ↑ "Specific probiotic strains are effective for genitourinary infections Townsend Letter for Doctors and Patients - Find Articles". Retrieved 2007-12-04.
- ↑ Hanson JM, McGregor JA, Hillier SL; et al. (2000). "Metronidazole for bacterial vaginosis. A comparison of vaginal gel vs. oral therapy". J Reprod Med. 45 (11): 889–96. PMID 11127100.