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==Pathophysiology==
==Pathophysiology==
Vertebral osteomyelitis often attacks two vertebrae and the corresponding intervertebral disk, causing narrowing of the disc space between the [[vertebra]]e.<ref name="wheeless">{{cite book|last=Wheeless, III, M.D.|first=Clifford|title=Wheeless' Textbook of Orthopaedics|year=2011|publisher=Duke University Medical Center|location=Duke University|url=http://www.wheelessonline.com/ortho/vertebral_osteomyelitis}}</ref> A notable aspect of the disease is found in its ability to start anywhere in the body and spread to other regions through the bloodstream. A number of bacterial strains can enter the body in this manner, making the origin of the infection hard to trace; thus, for many patients with the infection, this characteristic can delay an accurate diagnosis and prolong suffering.
Vertebral osteomyelitis often attacks two vertebrae and the corresponding intervertebral disk, causing narrowing of the disc space between the [[vertebra]]e.<ref name="wheeless">{{cite book|last=Wheeless, III, M.D.|first=Clifford|title=Wheeless' Textbook of Orthopaedics|year=2011|publisher=Duke University Medical Center|location=Duke University|url=http://www.wheelessonline.com/ortho/vertebral_osteomyelitis}}</ref> A notable aspect of the disease is found in its ability to start anywhere in the body and spread to other regions through the bloodstream. A number of bacterial strains can enter the body in this manner, making the origin of the infection hard to trace; thus, for many patients with the infection, this characteristic can delay an accurate diagnosis and prolong suffering.
==Differentiating Vertebral osteomyelitis from other Diseases==
Diagnosis can also be complicated due to the disease's similarity to [[discitis]], commonly known as an infection of the disc space. Both diseases are characterized by a patient's inability to walk and concentrated back pain; however, patients with vertebral osteomyelitis often appear more ill than those with discitis.<ref name="ADC: Discitis">{{cite journal|last=National Center for Biotechnology Information|title=Discitis versus Vertebral Osteomyelitis|journal=Archives of Disease in Childhood|year=2000|month=October|volume=4|issue=83|pages=368|accessdate=March 27, 2012|pmc=1718514|pmid=10999882}}</ref> Additional measures may be called upon to rule out the possibility of discitis; such approaches include diagnosing the disease through various medical imaging techniques.


==References==
==References==

Revision as of 20:19, 20 December 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The term osteomyelitis describes any new infection in the bone and bone marrow. Vertebral osteomyelitis is a specific type of this disease; the term describes a rare bone infection concentrated in the spinal region.[1]

Classification

The infection can be classified as acute or chronic depending on the severity of the onset of the case,[2] where acute patients often experience better outcomes than those living with the chronic symptoms that are characteristic of the disease.

Pathophysiology

Vertebral osteomyelitis often attacks two vertebrae and the corresponding intervertebral disk, causing narrowing of the disc space between the vertebrae.[3] A notable aspect of the disease is found in its ability to start anywhere in the body and spread to other regions through the bloodstream. A number of bacterial strains can enter the body in this manner, making the origin of the infection hard to trace; thus, for many patients with the infection, this characteristic can delay an accurate diagnosis and prolong suffering.

Differentiating Vertebral osteomyelitis from other Diseases

Diagnosis can also be complicated due to the disease's similarity to discitis, commonly known as an infection of the disc space. Both diseases are characterized by a patient's inability to walk and concentrated back pain; however, patients with vertebral osteomyelitis often appear more ill than those with discitis.[4] Additional measures may be called upon to rule out the possibility of discitis; such approaches include diagnosing the disease through various medical imaging techniques.

References

  1. Carek, M.D., Peter (15). "Diagnosis and Management of Osteomyelitis". American Family Physician. 12 (63): 2413–2421. Retrieved March 27, 2012. Unknown parameter |month= ignored (help); Unknown parameter |coauthors= ignored (help); Check date values in: |date=, |year= / |date= mismatch (help)
  2. David Dugdale, III, M.D. (2010). A.D.A.M Medical Encyclopedia: Osteomyelitis. Bethesda, MD: United States National Library of Medicine. Retrieved 12 March 2012. Unknown parameter |coauthors= ignored (help)
  3. Wheeless, III, M.D., Clifford (2011). Wheeless' Textbook of Orthopaedics. Duke University: Duke University Medical Center.
  4. National Center for Biotechnology Information (2000). "Discitis versus Vertebral Osteomyelitis". Archives of Disease in Childhood. 4 (83): 368. PMC 1718514. PMID 10999882. Unknown parameter |month= ignored (help); |access-date= requires |url= (help)

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