MICU intern's survival guide vasopressors: Difference between revisions
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==Overview== | ==Overview== | ||
===Norepinephrine=== | ===Norepinephrine=== | ||
* Mechanism of action - Acts on both alpha1 (vasoconstriction of blood vessels) and beta1 receptors (increases cardiac output). | * '''Mechanism of action''' - Acts on both alpha1 (vasoconstriction of blood vessels) and beta1 receptors (increases cardiac output). | ||
* Indications: | * '''Indications:''' | ||
** [[Septic shock]] | ** [[Septic shock]] | ||
** [[Cardiogenic shock]] - Recent studies have shown that [[norepinephrine]] may be better than [[dopamine]] in [[cardiogenic shock]] due to a decreased risk of [[tachyarrhythmia]]s. | ** [[Cardiogenic shock]] - Recent studies have shown that [[norepinephrine]] may be better than [[dopamine]] in [[cardiogenic shock]] due to a decreased risk of [[tachyarrhythmia]]s. | ||
Revision as of 14:11, 28 December 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Norepinephrine
- Mechanism of action - Acts on both alpha1 (vasoconstriction of blood vessels) and beta1 receptors (increases cardiac output).
- Indications:
- Septic shock
- Cardiogenic shock - Recent studies have shown that norepinephrine may be better than dopamine in cardiogenic shock due to a decreased risk of tachyarrhythmias.
- In cases where the type of shock is unclear, norepinephrine can be tried as a first line agent.
- Doses - 1-30 mcg/min.