MICU intern's survival guide vasopressors: Difference between revisions
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===Vasopressin=== | ===Vasopressin=== | ||
===Dopamine=== | ===Dopamine=== | ||
* '''Mechanism of action''' - Acts on both alpha1 (vasoconstriction of blood vessels) and beta1 receptors (increases cardiac output). | |||
* Its action is dose dependent. At low doses it predominantly acts on cardiac receptors (1-10 mcg/min) with less vasoconstriction activities. | |||
* '''Indications:''' | |||
** [[Septic shock]] | |||
** [[Cardiogenic shock]] - Recent studies have shown that [[norepinephrine]] may be better than [[dopamine]] in [[cardiogenic shock]] due to a decreased risk of [[tachyarrhythmia]]s. | |||
** In cases where the type of shock is unclear, [[norepinephrine]] can be tried as a first line agent. | |||
** Doses - 1-30 mcg/min. | |||
===Phenylephrine=== | ===Phenylephrine=== | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} {{WS}} | {{WH}} {{WS}} | ||
Revision as of 14:13, 28 December 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Norepinephrine
- Mechanism of action - Acts on both alpha1 (vasoconstriction of blood vessels) and beta1 receptors (increases cardiac output).
- Indications:
- Septic shock
- Cardiogenic shock - Recent studies have shown that norepinephrine may be better than dopamine in cardiogenic shock due to a decreased risk of tachyarrhythmias.
- In cases where the type of shock is unclear, norepinephrine can be tried as a first line agent.
- Doses - 1-30 mcg/min.
Dobutamine
Vasopressin
Dopamine
- Mechanism of action - Acts on both alpha1 (vasoconstriction of blood vessels) and beta1 receptors (increases cardiac output).
- Its action is dose dependent. At low doses it predominantly acts on cardiac receptors (1-10 mcg/min) with less vasoconstriction activities.
- Indications:
- Septic shock
- Cardiogenic shock - Recent studies have shown that norepinephrine may be better than dopamine in cardiogenic shock due to a decreased risk of tachyarrhythmias.
- In cases where the type of shock is unclear, norepinephrine can be tried as a first line agent.
- Doses - 1-30 mcg/min.