Coronavirus overview: Difference between revisions
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==Historical Perspective== | ==Historical Perspective== | ||
Coronaviruses were first isolated from chickens in 1937. In 1965, Tyrrell and Bynoe used cultures of human ciliated embryonal trachea to propagate the first human coronavirus (HCoV) in vitro. There are now approximately 15 species in this family, which infect not only man but cattle, pigs, rodents, cats, dogs and birds (some are serious veterinary pathogens, especially chickens).<ref name="urlCoronavirus - MicrobeWiki">{{cite web |url=http://microbewiki.kenyon.edu/index.php/Coronavirus |title=Coronavirus - MicrobeWiki |format= |work= |accessdate=2012-12-28}}</ref> | Coronaviruses were first isolated from chickens in 1937. In 1965, Tyrrell and Bynoe used cultures of human ciliated embryonal trachea to propagate the first human coronavirus (HCoV) in vitro. There are now approximately 15 species in this family, which infect not only man but cattle, pigs, rodents, cats, dogs and birds (some are serious veterinary pathogens, especially chickens).<ref name="urlCoronavirus - MicrobeWiki">{{cite web |url=http://microbewiki.kenyon.edu/index.php/Coronavirus |title=Coronavirus - MicrobeWiki |format= |work= |accessdate=2012-12-28}}</ref> | ||
==Epidemiology and Demographics== | |||
Coronaviruses have a worldwide distribution, causing 10-15% of [[common cold]] cases. Infections show a seasonal pattern with most cases occurring in the winter months.<ref name="urlHuman Coronavirus - Pathogen Safety Data Sheets">{{cite web |url=http://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/coronavirus-eng.php |title=Human Coronavirus - Pathogen Safety Data Sheets |format= |work= |accessdate=2012-12-28}}</ref> Coronavirus infection is very common and occurs worldwide. The incidence of infection is strongly seasonal, with the greatest incidence in children in winter. Adult infections are less common. The number of coronavirus serotypes and the extent of antigenic variation is unknown. Re-infections appear to occur throughout life, implying multiple serotypes (at least four are known) and/or antigenic variation, hence the prospects for [[immunization]] appear bleak. | |||
==References== | ==References== | ||
Revision as of 03:55, 3 January 2013
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Coronavirus Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Coronavirus overview On the Web |
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American Roentgen Ray Society Images of Coronavirus overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Overview
Coronavirus is a genus of animal virus belonging to the family Coronaviridae.[1]
Historical Perspective
Coronaviruses were first isolated from chickens in 1937. In 1965, Tyrrell and Bynoe used cultures of human ciliated embryonal trachea to propagate the first human coronavirus (HCoV) in vitro. There are now approximately 15 species in this family, which infect not only man but cattle, pigs, rodents, cats, dogs and birds (some are serious veterinary pathogens, especially chickens).[2]
Epidemiology and Demographics
Coronaviruses have a worldwide distribution, causing 10-15% of common cold cases. Infections show a seasonal pattern with most cases occurring in the winter months.[3] Coronavirus infection is very common and occurs worldwide. The incidence of infection is strongly seasonal, with the greatest incidence in children in winter. Adult infections are less common. The number of coronavirus serotypes and the extent of antigenic variation is unknown. Re-infections appear to occur throughout life, implying multiple serotypes (at least four are known) and/or antigenic variation, hence the prospects for immunization appear bleak.
References
- ↑ Thiel V (editor). (2007). Coronaviruses: Molecular and Cellular Biology (1st ed. ed.). Caister Academic Press. ISBN 978-1-904455-16-5.