Brugada syndrome historical perspective: Difference between revisions
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Brugada syndorme was potentially first seen on [[EKG]] in survivors of cardiac arrest in 1989, but it was not until 1992 that the Brugada brothers recognized it as a distinct clinical entity which could cause [[sudden death]] by [[ventricular fibrillation]]. | Brugada syndorme was potentially first seen on [[EKG]] in survivors of cardiac arrest in 1989, but it was not until 1992 that the Brugada brothers recognized it as a distinct clinical entity which could cause [[sudden death]] by [[ventricular fibrillation]]. | ||
==Historical Perspective== | ==Historical Perspective== | ||
The Brugada brothers were the first to describe the characteristic ECG findings and link them to sudden death. | The Brugada brothers were the first to describe the characteristic ECG findings and link them to sudden death. Before that the characteristic ECG findings were often mistaken for a [[right ventricular myocardial infarction]]. In 1953 a publication by Oscher mentioned that despite being mistaken for right ventricular myocardial infarction, the ECG findings were not associated with myocardial ischemia.<ref name="pmid13104407">{{cite journal |author=OSHER HL, WOLFF L |title=Electrocardiographic pattern simulating acute myocardial injury |journal=[[The American Journal of the Medical Sciences]] |volume=226 |issue=5 |pages=541–5 |year=1953 |month=November |pmid=13104407 |doi= |url= |issn= |accessdate=2012-10-13}}</ref> | ||
Before that the characteristic ECG findings were often mistaken for a [[right ventricular myocardial infarction]]. In 1953 a publication by Oscher mentioned that despite being mistaken for right ventricular myocardial infarction, the ECG findings were not associated with myocardial ischemia.<ref name="pmid13104407">{{cite journal |author=OSHER HL, WOLFF L |title=Electrocardiographic pattern simulating acute myocardial injury |journal=[[The American Journal of the Medical Sciences]] |volume=226 |issue=5 |pages=541–5 |year=1953 |month=November |pmid=13104407 |doi= |url= |issn= |accessdate=2012-10-13}}</ref> | |||
Although the ECG findings of Brugada syndrome were first reported<ref>Martini B, Nava A, Thiene G, Buja GF, Canciani B, Scognamiglio R, Daliento L, Dalla Volta S. Ventricular fibrillation without apparent heart disease: description of six cases. Am Heart J 1989 Dec;118(6):1203-9 PMID 2589161</ref> among survivors of cardiac arrest in 1989, it was only in 1992 that the Brugada brothers<ref>Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol. 1992 Nov 15;20(6):1391-6. PMID 1309182</ref> recognized it as a distinct clinical entity, causing sudden [[death]] by causing [[ventricular fibrillation]]. | Although the ECG findings of Brugada syndrome were first reported<ref>Martini B, Nava A, Thiene G, Buja GF, Canciani B, Scognamiglio R, Daliento L, Dalla Volta S. Ventricular fibrillation without apparent heart disease: description of six cases. Am Heart J 1989 Dec;118(6):1203-9 PMID 2589161</ref> among survivors of cardiac arrest in 1989, it was only in 1992 that the Brugada brothers<ref>Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol. 1992 Nov 15;20(6):1391-6. PMID 1309182</ref> recognized it as a distinct clinical entity, causing sudden [[death]] by causing [[ventricular fibrillation]]. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Brugada syndorme was potentially first seen on EKG in survivors of cardiac arrest in 1989, but it was not until 1992 that the Brugada brothers recognized it as a distinct clinical entity which could cause sudden death by ventricular fibrillation.
Historical Perspective
The Brugada brothers were the first to describe the characteristic ECG findings and link them to sudden death. Before that the characteristic ECG findings were often mistaken for a right ventricular myocardial infarction. In 1953 a publication by Oscher mentioned that despite being mistaken for right ventricular myocardial infarction, the ECG findings were not associated with myocardial ischemia.[1]
Although the ECG findings of Brugada syndrome were first reported[2] among survivors of cardiac arrest in 1989, it was only in 1992 that the Brugada brothers[3] recognized it as a distinct clinical entity, causing sudden death by causing ventricular fibrillation.
References
- ↑ OSHER HL, WOLFF L (1953). "Electrocardiographic pattern simulating acute myocardial injury". The American Journal of the Medical Sciences. 226 (5): 541–5. PMID 13104407. Unknown parameter
|month=ignored (help);|access-date=requires|url=(help) - ↑ Martini B, Nava A, Thiene G, Buja GF, Canciani B, Scognamiglio R, Daliento L, Dalla Volta S. Ventricular fibrillation without apparent heart disease: description of six cases. Am Heart J 1989 Dec;118(6):1203-9 PMID 2589161
- ↑ Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol. 1992 Nov 15;20(6):1391-6. PMID 1309182