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Revision as of 17:42, 21 January 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Diabetic nephropathy is one of the most common causes of chronic renal failure in the United States, responsible for 45 % of patients on dialysis.
Epidemiology and Demographics
The syndrome can be seen in patients with chronic diabetes (15 years or more after onset), so patients are usually of older age (between 50 and 70 years old). The disease is progressive and may cause death two or three years after the initial lesions, and is more frequent in men. Diabetic nephropathy is the most common cause of chronic kidney failure and end-stage kidney disease in the United States. People with both type 1 and type 2 diabetes are at risk. The risk is higher if blood-glucose levels are poorly controlled. Further, once nephropathy develops, the greatest rate of progression is seen in patients with poor control of their blood pressure. Also people with high cholesterol level in their blood have much more risk than others.