Aortic dissection laboratory findings: Difference between revisions
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{{Template:Aortic dissection}} | {{Template:Aortic dissection}} | ||
{{CMG}} ; '''Associate Editor-In-Chief:''' {{CZ}} | {{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}} | ||
==Overview== | ==Overview== | ||
Routine blood work is usually not helpful and should not delay definitive [[diagnosis|diagnostic]] studies such as a [[CT]] scan and treatment. | Routine blood work is usually not helpful and should not delay definitive [[diagnosis|diagnostic]] studies such as a [[CT]] scan and treatment. | ||
==Laboratory Findings== | |||
==Complete Blood Count== | ===Complete Blood Count=== | ||
[[Hemolysis]] can be present as a result of blood in the [[false lumen]]. | [[Hemolysis]] can be present as a result of blood in the [[false lumen]]. | ||
===Biomarker Studies=== | |||
==Biomarker Studies== | |||
*There has been one report using a [[smooth muscle]] [[myosin]] heavy chain [[immunoassay]] to help [[diagnosis|diagnose]] [[aortic]] dissection. They report that a level > 10 ng/ml within the first 12h is 90% [[sensitivity|sensitive]] and 97% [[specificity|specific]]. This finding needs to be confirmed in other trials however. | *There has been one report using a [[smooth muscle]] [[myosin]] heavy chain [[immunoassay]] to help [[diagnosis|diagnose]] [[aortic]] dissection. They report that a level > 10 ng/ml within the first 12h is 90% [[sensitivity|sensitive]] and 97% [[specificity|specific]]. This finding needs to be confirmed in other trials however. | ||
*The presence of an elevated [[CK MB]] may indicate the presence of concomitant [[acute myocardial infarction]] (often a [[right coronary artery]] occlusion due to occlusion of the [[ostium]] of the [[RCA]] by the dissection). | *The presence of an elevated [[CK MB]] may indicate the presence of concomitant [[acute myocardial infarction]] (often a [[right coronary artery]] occlusion due to occlusion of the [[ostium]] of the [[RCA]] by the dissection). | ||
===Urinalysis=== | |||
==Urinalysis== | |||
*[[Hematuria]] may be present and may indicate the presence of [[renal infarction]]. | *[[Hematuria]] may be present and may indicate the presence of [[renal infarction]]. | ||
Revision as of 19:30, 25 January 2013
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Aortic dissection Microchapters |
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Diagnosis |
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Treatment |
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Special Scenarios |
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Case Studies |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Overview
Routine blood work is usually not helpful and should not delay definitive diagnostic studies such as a CT scan and treatment.
Laboratory Findings
Complete Blood Count
Hemolysis can be present as a result of blood in the false lumen.
Biomarker Studies
- There has been one report using a smooth muscle myosin heavy chain immunoassay to help diagnose aortic dissection. They report that a level > 10 ng/ml within the first 12h is 90% sensitive and 97% specific. This finding needs to be confirmed in other trials however.
- The presence of an elevated CK MB may indicate the presence of concomitant acute myocardial infarction (often a right coronary artery occlusion due to occlusion of the ostium of the RCA by the dissection).
Urinalysis
- Hematuria may be present and may indicate the presence of renal infarction.