Arteriovenous malformations pathophysiology: Difference between revisions
No edit summary |
|||
| Line 35: | Line 35: | ||
[[Category:Neurology]] | [[Category:Neurology]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Needs content]] | |||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Revision as of 14:41, 31 January 2013
|
Arteriovenous malformations Microchapters |
|
Differentiating Arteriovenous malformations from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Arteriovenous malformations pathophysiology On the Web |
|
American Roentgen Ray Society Images of Arteriovenous malformations pathophysiology |
|
Directions to Hospitals Treating Arteriovenous malformations |
|
Risk calculators and risk factors for Arteriovenous malformations pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]
Overview
Arteries and veins are part of the human cardiovascular system. Normally, the arteries in the vascular system carry oxygen-rich blood at a relatively high pressure. Structurally, arteries divide and sub-divide repeatedly, eventually forming a sponge-like capillary bed. Blood moves through the capillaries, giving up oxygen and taking up waste products from the surrounding cells. Capillaries successively join together, one upon the other, to form the veins that carry blood away at a relatively low pressure. The heart acts to pump blood from the low pressure veins to the high pressure arteries.
Pathophysiology
If the capillary bed is thought of as a sponge, then an AVM is the rough equivalent of inserting a tangle of drinking straw|flexible soda straws from artery to vein through that sponge. On an arteriogram, an AVM often resemble a tangle of spaghetti noodles. This tangle of blood vessels forms a relatively direct connection between high pressure arteries and low pressure veins and bypasses the capillary bed.
The result is a collection of blood vessels with abnormal connections and no capillaries. This collection, often called a nidus, can be extremely fragile and prone to bleeding. This bleeding can be catastrophic if it occurs in the brain, the lung or the gastrointestinal tract.
AVMs can occur in various parts of the body
- Brain, causing a cerebral arteriovenous malformation
- Spleen[1]
- Lung[2]
- Kidney[3]
- Spinal cord[4]
- Liver[5]
- Intercostal space[6]
- Iris[7]
- Spermatic cord[8]
Genetics
Can occur due to autosomal dominant diseases, such as hereditary hemorrhagic telangiectasia
Microscopic Pathology
References
- ↑ Agrawal A, Whitehouse R, Johnson RW, Augustine T (2006). "Giant splenic artery aneurysm associated with arteriovenous malformation". J. Vasc. Surg. 44 (6): 1345–9. doi:10.1016/j.jvs.2006.06.049. PMID 17145440. Retrieved 2008-06-01. Unknown parameter
|month=ignored (help) - ↑ Chowdhury UK, Kothari SS, Bishnoi AK, Gupta R, Mittal CM, Reddy S (2008). "Successful Lobectomy for Pulmonary Arteriovenous Malformation Causing Recurrent Massive Haemoptysis". Heart Lung Circ. doi:10.1016/j.hlc.2007.11.142. PMID 18294908. Retrieved 2008-06-01. Unknown parameter
|month=ignored (help) - ↑ Barley FL, Kessel D, Nicholson T, Robertson I (2006). "Selective embolization of large symptomatic iatrogenic renal transplant arteriovenous fistula". Cardiovasc Intervent Radiol. 29 (6): 1084–7. doi:10.1007/s00270-005-0265-z. PMID 16794894.
- ↑ Kishi K, Shirai S, Sonomura T, Sato M (2005). "Selective conformal radiotherapy for arteriovenous malformation involving the spinal cord". Br J Radiol. 78 (927): 252–4. PMID 15730991. Unknown parameter
|month=ignored (help) - ↑ Bauer T, Britton P, Lomas D, Wight DG, Friend PJ, Alexander GJ (1995). "Liver transplantation for hepatic arteriovenous malformation in hereditary haemorrhagic telangiectasia". J. Hepatol. 22 (5): 586–90. PMID 7650340. Retrieved 2008-06-01. Unknown parameter
|month=ignored (help) - ↑ Rivera PP, Kole MK, Pelz DM, Gulka IB, McKenzie FN, Lownie SP (2006). "Congenital intercostal arteriovenous malformation". AJR Am J Roentgenol. 187 (5): W503–6. doi:10.2214/AJR.05.0367. PMID 17056881. Unknown parameter
|month=ignored (help) - ↑ Shields JA, Streicher TF, Spirkova JH, Stubna M, Shields CL (2006). "Arteriovenous malformation of the iris in 14 cases". Arch. Ophthalmol. 124 (3): 370–5. doi:10.1001/archopht.124.3.370. PMID 16534057. Unknown parameter
|month=ignored (help) - ↑ Sountoulides P, Bantis A, Asouhidou I, Aggelonidou H (2007). "Arteriovenous malformation of the spermatic cord as the cause of acute scrotal pain: a case report". J Med Case Reports. 1: 110. doi:10.1186/1752-1947-1-110. PMID 17939869.