Altitude sickness laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Chronic mountain sickness (CMS) is characterised by [[polycythemia]] (increased [[hematocrit]]) and [[hypoxemia]] which both decrease on descent from altitude. CMS is believed to arise because of an excessive production of red blood cells, which increases the oxygen carrying capacity of the blood | Chronic mountain sickness (CMS) is characterised by [[polycythemia]] (increased [[hematocrit]]) and [[hypoxemia]] which both decrease on descent from altitude. CMS is believed to arise because of an excessive production of red blood cells, which increases the oxygen carrying capacity of the blood but may cause increased blood viscosity and uneven blood flow through the lungs ([[V/Q mismatch]]). However, CMS is also considered an adaptation of pulmonary and heart disease to life under chronic hypoxia at altitude<ref name="pmid17072074">{{cite journal| author=Zubieta-Castillo G, Zubieta-Calleja GR, Zubieta-Calleja L| title=Chronic mountain sickness: the reaction of physical disorders to chronic hypoxia. | journal=J Physiol Pharmacol | year= 2006 | volume= 57 Suppl 4 | issue= | pages= 431-42 | pmid=17072074 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17072074 }} </ref>. | ||
==References== | ==References== | ||
Revision as of 14:21, 4 February 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Chronic mountain sickness (CMS) is characterised by polycythemia (increased hematocrit) and hypoxemia which both decrease on descent from altitude. CMS is believed to arise because of an excessive production of red blood cells, which increases the oxygen carrying capacity of the blood but may cause increased blood viscosity and uneven blood flow through the lungs (V/Q mismatch). However, CMS is also considered an adaptation of pulmonary and heart disease to life under chronic hypoxia at altitude[1].
References
- ↑ Zubieta-Castillo G, Zubieta-Calleja GR, Zubieta-Calleja L (2006). "Chronic mountain sickness: the reaction of physical disorders to chronic hypoxia". J Physiol Pharmacol. 57 Suppl 4: 431–42. PMID 17072074.