Toxic epidermal necrolysis causes: Difference between revisions
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==Overview== | ==Overview== | ||
Toxic epidermal necrolysis is a rare and usually severe adverse reaction to certain drugs. History of medication use exists in over 95% of patients with TEN. | Toxic epidermal necrolysis is a rare and usually severe adverse reaction to certain drugs. History of medication use exists in over 95% of patients with TEN. The drugs most often implicated in TEN are antibiotics such as sulfonamides; [[nonsteroidal anti-inflammatory drugs]]; [[allopurinol]],[[antiretroviral drugs]]; and [[corticosteroids]]; and [[anticonvulsant]]s such as [[phenobarbital]], [[phenytoin]], [[carbamazepine]], and [[valproic acid]]. The condition might also result from immunizations, infection with agents such as ''[[Mycoplasma pneumoniae]]'' or the [[herpes virus]]; and [[Organ transplant|transplant]]s of [[bone marrow]] or organs. | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Revision as of 00:13, 11 February 2013
Toxic epidermal necrolysis Microchapters |
Differentiating Toxic Epidermal Necrolysis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Toxic epidermal necrolysis is a rare and usually severe adverse reaction to certain drugs. History of medication use exists in over 95% of patients with TEN. The drugs most often implicated in TEN are antibiotics such as sulfonamides; nonsteroidal anti-inflammatory drugs; allopurinol,antiretroviral drugs; and corticosteroids; and anticonvulsants such as phenobarbital, phenytoin, carbamazepine, and valproic acid. The condition might also result from immunizations, infection with agents such as Mycoplasma pneumoniae or the herpes virus; and transplants of bone marrow or organs.