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{{Meningococcemia}}
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{{CMG}}; '''Associate Editor(s)-In-Chief:''' {{CZ}}
{{CMG}}; '''Associate Editor(s)-In-Chief:''' {{CZ}}
==Pathophysiology==
==Pathophysiology==
* Transmission through respiratory secretions from a nasopharyngeal carrier case-patient.
* Transmission through respiratory secretions from a nasopharyngeal carrier case-patient.

Revision as of 03:54, 19 February 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Pathophysiology

  • Transmission through respiratory secretions from a nasopharyngeal carrier case-patient.
  • Shock is due to lipooligosaccharide which is a potent toxin. This toxin initiates release of inflammatory cytokines, reactive oxygen radicals, prostaglandins, arachidonic acid, complement activated products, platelet aggregating factor, and perhaps nitric oxide.

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