Meningococcemia pathophysiology: Difference between revisions
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{{Meningococcemia}} | {{Meningococcemia}} | ||
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{{CMG}}; '''Associate Editor(s)-In-Chief:''' {{CZ}} | {{CMG}}; '''Associate Editor(s)-In-Chief:''' {{CZ}} | ||
==Pathophysiology== | ==Pathophysiology== | ||
* Transmission through respiratory secretions from a nasopharyngeal carrier case-patient. | * Transmission through respiratory secretions from a nasopharyngeal carrier case-patient. |
Revision as of 03:54, 19 February 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Pathophysiology
- Transmission through respiratory secretions from a nasopharyngeal carrier case-patient.
- Shock is due to lipooligosaccharide which is a potent toxin. This toxin initiates release of inflammatory cytokines, reactive oxygen radicals, prostaglandins, arachidonic acid, complement activated products, platelet aggregating factor, and perhaps nitric oxide.