Tuberous sclerosis surgery: Difference between revisions
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==Overview== | ==Overview== | ||
<br /> | |||
== Surgical Treatment == | |||
=== Epilepsy === | |||
* [[Vagal nerve stimulation]] or surgical resection of CNS lesion responsible for the [[epilepsy]] may be used.<ref name=":0">Henske, Elizabeth P., et al. "Tuberous sclerosis complex." ''Nature reviews Disease primers'' 2.1 (2016): 1-18.</ref> | |||
=== Angiomyolipoma === | |||
* Treatment is done in a pre-emptive manner to prevent bleeding, reduce tumor size or slow its growth. Percutaneous [[Therapeutic embolization|embolization]] (which may present with postembolization syndrome) and nephron-sparing surgical resection are possible treatments.<ref name=":0" /> | |||
=== Subependymal Giant Cell Astrocytoma === | |||
* Surgical resection is the most performed treatment, but may complicate with incomplete resection, hemorrhage, infection and cerebrospinal fluid obstruction.<ref name=":0" /> | |||
=== Skin Lesions === | |||
For TSC-associated skin lesions, the following surgical treatments may be performed: | |||
* Ablation with pulse laser dye or [[CO2]]; | |||
* Surgery | |||
==References== | ==References== |
Revision as of 23:16, 19 June 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Surgical Treatment
Epilepsy
- Vagal nerve stimulation or surgical resection of CNS lesion responsible for the epilepsy may be used.[1]
Angiomyolipoma
- Treatment is done in a pre-emptive manner to prevent bleeding, reduce tumor size or slow its growth. Percutaneous embolization (which may present with postembolization syndrome) and nephron-sparing surgical resection are possible treatments.[1]
Subependymal Giant Cell Astrocytoma
- Surgical resection is the most performed treatment, but may complicate with incomplete resection, hemorrhage, infection and cerebrospinal fluid obstruction.[1]
Skin Lesions
For TSC-associated skin lesions, the following surgical treatments may be performed:
- Ablation with pulse laser dye or CO2;
- Surgery