Pseudomembranous colitis CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

CT scan

• Common CT findings include wall thickening, low-attenuation mural thickening corresponding to mucosal and submucosal edema, the accordion sign, the target sign, double halo sign, pericolonic stranding, and ascites.

• • The target sign, which consists of two or three concentric rings of different attenuation, indicates mucosal hyperemia and submucosal edema or inflammation. The rings of varying attenuation are best appreciated during the arterial phase of enhancement.
  • The accordion sign is seen when orally administered contrast material becomes trapped between markedly thickened haustral folds, giving the appearance of alternating bands of high attenuation (contrast material) and low attenuation (edematous haustra). This sign is highly suggestive of PMC, although it is usually seen only in advanced cases.