Dermatofibroma pathophysiology: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
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==References== | |||
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Revision as of 14:44, 1 April 2013
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Pathophysiology
- Some physicians and researchers believe dermatofibromas form as a reaction to previous injuries such as insect bites or thorn pricks.
- Dermatofibromas are composed of disordered collagen laid down by fibroblasts.
Immunohistochemical staining
| Neoplasm | CD34[1] | Stromelysin-3[2] | Factor XIIIa[3] |
|---|---|---|---|
| Dermatofibroma | + | + | + |
| Dermatofibrosarcoma protuberans | + | - | - |
References
- ↑ Invalid
<ref>tag; no text was provided for refs namedBolognia - ↑ Kim HJ, Lee JY, Kim SH; et al. (2007). "Stromelysin-3 expression in the differential diagnosis of dermatofibroma and dermatofibrosarcoma protuberans: comparison with factor XIIIa and CD34". Br. J. Dermatol. 157 (2): 319–24. doi:10.1111/j.1365-2133.2007.08033.x. PMID 17596171. Unknown parameter
|month=ignored (help) - ↑ http://emedicine.medscape.com/article/1056742-overview