High density lipoprotein epidemiology and demographics: Difference between revisions
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===Family History=== | ===Family History=== | ||
Patients with lipid metabolism disorders more often tend to have a family history of [[dyslipidemia]]. | Patients with lipid metabolism disorders more often tend to have a family history of [[dyslipidemia]]<ref name="pmid1534286">{{cite journal |author=Genest JJ, Martin-Munley SS, McNamara JR, ''et al.'' |title=Familial lipoprotein disorders in patients with premature coronary artery disease |journal=[[Circulation]] |volume=85 |issue=6 |pages=2025–33 |year=1992 |month=June |pmid=1534286 |doi= |url=}}</ref>. | ||
===Coronary artery disease=== | ===Coronary artery disease=== | ||
Revision as of 20:40, 26 April 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]; Raviteja Guddeti, M.B.B.S. [3]
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Overview
Epidemiological studies have shown that high concentrations of HDL (over 60 mg/dL) have protective value against cardiovascular diseases such as ischemic stroke and myocardial infarction. Low concentrations of HDL (below 40 mg/dL for men, below 50 mg/dL for women) are a positive risk factor for these atherosclerotic diseases.
Data from the landmark Framingham Heart Study showed that for a given level of LDL, the risk of heart disease increases 10-fold as the HDL varies from high to low. Conversely, for a fixed level of HDL, the risk increases 3-fold as LDL varies from low to high.
Epidemiology and Demographics
Age
The prevalence of dyslipidemia is highest in men ages 55 to 60 years old and before 65 years in women.
Gender
Men tend to have noticeably lower HDL levels, with smaller size and lower cholesterol content, than women. Men also have an increased incidence of atherosclerotic heart disease.
Family History
Patients with lipid metabolism disorders more often tend to have a family history of dyslipidemia[1].
Coronary artery disease
The prevalence of dyslipidemia is higher in patients with coronary artery disease than in those with no coronary disease.
References
- ↑ Genest JJ, Martin-Munley SS, McNamara JR; et al. (1992). "Familial lipoprotein disorders in patients with premature coronary artery disease". Circulation. 85 (6): 2025–33. PMID 1534286. Unknown parameter
|month=ignored (help)