Coma overview: Difference between revisions
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==Overview== | ==Overview== | ||
In [[medicine]], a '''coma''' (from the [[Greek language|Greek]] {{polytonic|κῶμα}} ''koma'', meaning deep sleep) is a profound state of [[unconsciousness]]. A comatose patient cannot be awakened, fails to respond normally to pain or light, does not have sleep-wake cycles, and does not take voluntary actions. Coma may result from a variety of conditions, including [[intoxication]], [[metabolism|metabolic]] abnormalities, central nervous system diseases, acute neurologic injuries such as [[stroke]], and [[Hypoxia (medical)|hypoxia]]. It may also be deliberately [[induced coma|induced]] by pharmaceutical agents in order to preserve higher brain function following another form of brain trauma, or to save the patient from extreme pain during healing of injuries or diseases. A coma may also result from immense [[head trauma]] caused by something like a car accident or a series of very severe [[concussion]]s. The underlying cause of the coma is bilateral damage to the [[reticular formation]] of the [[midbrain]], which is important in regulating sleep.<ref> The Human Brain: an introduction to its functional anatomy 5th ed by J Nolte chpt 11 pp262-290 </ref> | In [[medicine]], a '''coma''' (from the [[Greek language|Greek]] {{polytonic|κῶμα}} ''koma'', meaning deep sleep) is a profound state of [[unconsciousness]]. A comatose patient cannot be awakened, fails to respond normally to pain or light, does not have sleep-wake cycles, and does not take voluntary actions. Coma may result from a variety of conditions, including [[intoxication]], [[metabolism|metabolic]] abnormalities, central nervous system diseases, acute neurologic injuries such as [[stroke]], and [[Hypoxia (medical)|hypoxia]]. It may also be deliberately [[induced coma|induced]] by pharmaceutical agents in order to preserve higher brain function following another form of brain trauma, or to save the patient from extreme pain during healing of injuries or diseases. A coma may also result from immense [[head trauma]] caused by something like a car accident or a series of very severe [[concussion]]s. The underlying cause of the coma is bilateral damage to the [[reticular formation]] of the [[midbrain]], which is important in regulating sleep.<ref> The Human Brain: an introduction to its functional anatomy 5th ed by J Nolte chpt 11 pp262-290 </ref> | ||
==Diagnosis== | |||
===Physical Examination=== | |||
Neurological examination and eye examination are very useful to identify underlying problem in the brain. | |||
===Laboratory Findings=== | |||
Laboratory tests include the check of liver function, kidney function, glucose levels, thyroid function, even the presence of any toxins. The results of the various lab tests may provide clues to detect some metabolic diseases which can cause coma. | |||
===CT=== | |||
CT images can be used to detect the abnormalities in the [[brain]]. | |||
===MRI=== | |||
MRI images can be used to detect the abnormalities in the [[brain]]. | |||
===Other Diagnostic Studies=== | |||
[[Electroencephalography]] ([[EEG]]) test can demonstrate the electrical activity in the brain and be used to rule out [[seizure]]s. | |||
===Surgery=== | |||
Treatments depend on the underlying cause. Emergent [[surgery]] is needed for a hemorrhage stroke. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 13:54, 29 April 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S.[4]
Overview
In medicine, a coma (from the Greek Template:Polytonic koma, meaning deep sleep) is a profound state of unconsciousness. A comatose patient cannot be awakened, fails to respond normally to pain or light, does not have sleep-wake cycles, and does not take voluntary actions. Coma may result from a variety of conditions, including intoxication, metabolic abnormalities, central nervous system diseases, acute neurologic injuries such as stroke, and hypoxia. It may also be deliberately induced by pharmaceutical agents in order to preserve higher brain function following another form of brain trauma, or to save the patient from extreme pain during healing of injuries or diseases. A coma may also result from immense head trauma caused by something like a car accident or a series of very severe concussions. The underlying cause of the coma is bilateral damage to the reticular formation of the midbrain, which is important in regulating sleep.[1]
Diagnosis
Physical Examination
Neurological examination and eye examination are very useful to identify underlying problem in the brain.
Laboratory Findings
Laboratory tests include the check of liver function, kidney function, glucose levels, thyroid function, even the presence of any toxins. The results of the various lab tests may provide clues to detect some metabolic diseases which can cause coma.
CT
CT images can be used to detect the abnormalities in the brain.
MRI
MRI images can be used to detect the abnormalities in the brain.
Other Diagnostic Studies
Electroencephalography (EEG) test can demonstrate the electrical activity in the brain and be used to rule out seizures.
Surgery
Treatments depend on the underlying cause. Emergent surgery is needed for a hemorrhage stroke.
References
- ↑ The Human Brain: an introduction to its functional anatomy 5th ed by J Nolte chpt 11 pp262-290