Thrombophilia causes: Difference between revisions

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| '''Drug Side Effect'''
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|bgcolor="Beige"| • [[Asparaginase]] • [[Bevacizumab]] • [[Combined oral contraceptive pill]] • [[Cyproterone]] • [[Diethylstilboestrol]] • [[Drospirenone]] • [[Eltrombopag]] • [[Erythropoietin]] • [[Ethinylestradiol]] • [[Fosfestrol]] • [[Granulocyte-macrophage colony stimulating factor]] • [[Heparin]] • [[Hormone replacement therapy]] • [[Lenalidomide]] • [[Peginesatide]] • [[Polyestradiol]] • [[Raloxifene]] • [[Strontium ranelate]] • [[Tamoxifen]] • [[Tobacco smoking]] • [[Tranexamic acid]] • [[Vorinostat]]
|bgcolor="Beige"| • [[Asparaginase]] • [[bevacizumab]] • [[combined oral contraceptive pill]] • [[certolizumab pegol]] • [[Ccproterone]] • [[diethylstilboestrol]] • [[drospirenone]] • [[eltrombopag]] • [[erythropoietin]] • [[ethinylestradiol]] • [[fosfestrol]] • [[granulocyte-macrophage colony stimulating factor]] • [[heparin]] • [[hormone replacement therapy]] • [[lenalidomide]] • [[peginesatide]] • [[polyestradiol]] • [[raloxifene]] • [[strontium ranelate]] • [[tamoxifen]] • [[tobacco smoking]] • [[tranexamic acid]] • [[vorinostat]]
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Revision as of 21:20, 27 April 2015


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Causes

Inherited

In a cohort study. the population attributable risk of venous thromboembolism was:[1]

Common types:

Rare forms:

Acquired

Causes of Thrombophilia by Organ System

Cardiovascular • Cerebral vein thrombosis • Acute myocardial infarction • Deep vein thrombophlebitis • Portal vein thrombosis • Pelvic thrombophlebitis
Drug Side Effect • Asparaginase • bevacizumab • combined oral contraceptive pill • certolizumab pegol • Ccproterone • diethylstilboestrol • drospirenone • eltrombopag • erythropoietin • ethinylestradiol • fosfestrol • granulocyte-macrophage colony stimulating factor • heparin • hormone replacement therapy • lenalidomide • peginesatide • polyestradiol • raloxifene • strontium ranelate • tamoxifen • tobacco smoking • tranexamic acid • vorinostat
Endocrine • Hyperosmolar non-ketotic diabetic coma
Gastroenterologic • Acute pancreatitis • Portal hypertension
Genetic Congenital Dysfibrinogenemia • Factor II mutation • Hereditary thrombophlebitis • Antithrombin III deficiency • Factor V Leiden mutation • Protein C deficiency • Protein S deficiency • Klippel-Trenaunay syndrome • Klinefelter syndrome • Sickle cell disease • Carbohydrate-deficient glycoprotein syndrome type 1b • Factor XII deficiency • Haemoglobin SC disease • Hyperprothrombinemia 20210G-A • Plasminogen deficiency • Activated protein C resistance • CD59 antigen deficiency • Cystathionine beta-synthase deficiency
Hematologic • Polycythemia vera • Essential thrombocythemia • Myeloproliferative disease • Hyperviscosity syndrome • Paroxysmal Nocturnal Hemoglobinuria • Thrombocytosis • Raised homocysteine levels
Iatrogenic • Surgical complication
Infectious Disease • Intraperitoneal abscess • Acute peritonitis • Visceral abscess • Diverticulitis • Intravenous catheter infection
Musculoskeletal / Ortho • Orthopedic surgeries • Abdominal surgery
Nutritional / Metabolic • Cystathionuria • Homocystinuria • Methyltetrahydrofolate reductase deficiency • Metabolic Syndrome • Insulin resistance • Folic acid deficiency • Obesity
Obstetric/Gynecologic • Pregnancy • Puerperium period • Ovarian hyperstimulation syndrome
Oncologic • Malignancy • Peritoneal metastasis • Adenocarcinoma of cecum • Adenocarcinoma of colon • Occult malignancy • Leukemia • Pancreatic cancer • Glucagonoma
Renal / Electrolyte • Chronic renal failure • Paroxysmal Nocturnal Hemoglobinuria • Nephrotic syndrome
Rheum / Immune / Allergy • Antiphospholipid Syndrome • Circulating anticoagulant • Heparin induced thrombocytopenia • Inflammatory bowel disease • Crohn's disease• Behcet disease • Hughes-Stovin syndrome • Polyarteritis Nodosa • SLE
Trauma • Trauma • Abdominal trauma
Miscellaneous • Paraneoplastic syndrome • Hypereosinophilic syndrome • Immobility

References

  1. ↑ Sode BF, Allin KH, Dahl M, Gyntelberg F, Nordestgaard BG (2013). "Risk of venous thromboembolism and myocardial infarction associated with factor V Leiden and prothrombin mutations and blood type". CMAJ. 185 (5): E229–37. doi:10.1503/cmaj.121636. PMC 3602271. PMID 23382263.

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