Nephrotic syndrome causes: Difference between revisions

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Revision as of 16:47, 2 May 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Causes

Primary Causes

Primary causes of nephrotic syndrome are usually described by the histology, i.e. minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS) and membranous nephropathy (MN).

They are considered to be "diagnoses of exclusion", i.e. they are diagnosed only after secondary causes have been excluded.

Secondary Causes

Secondary causes of nephrotic syndrome have the same histologic patterns as the primary causes, though may exhibit some differences suggesting a secondary cause.

They are usually described by the underlying cause.

Secondary Causes by Histologic Pattern

Membranous nephropathy (MN)^[1]

Focal segmental glomerulosclerosis (FSGS)^[1]

Minimal change disease (MCD)^[1]

Drugs
Malignancy, especially Hodgkin's lymphoma

GN with Nephrotic Syndrome

Acute Glomerulonenephritis

Secondary

Miscellaneous

References

↑ ^1.0 ^1.1 ^1.2 Fogo AB, Bruijn JA. Cohen AH, Colvin RB, Jennette JC. Fundamentals of Renal Pathology. Springer. ISBN 978-0387-31126-5.

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[fogo-1] 1.0 ^1.1 ^1.2 Fogo AB, Bruijn JA. Cohen AH, Colvin RB, Jennette JC. Fundamentals of Renal Pathology. Springer. ISBN 978-0387-31126-5.

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