Cardiac amyloidosis echocardiography

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]: Aarti Narayan, M.B.B.S [3]; Cafer Zorkun, M.D., Ph.D. [4]

Overview

Transthoracic echocardiography is most commonly used in the initial evaluation of cardiac amyloidosis. The most common echocardiographic finding is thickening of the left ventricle.

Echocardiography

Findings on echocardiography include:

• Thickening of the left ventricle
• Granular or sparkling appearance of the myocardium secondary to amyloid deposition int he myocardium. This finding is especially seen best with two dimentional echocardiography.
• Thickening of interventricular septum
• Diastolic dysfunction
• Normal or reduced LV cavity
• Pericardial effusion
• RV hypertrophy
• Left atrial enlargement
• Thickened AV valves
• Right ventricular dilatation (poor prognostic marker indicating right heart failure)

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