Splenomegaly causes: Difference between revisions
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| '''''Removal of defective RBCs''''' | | '''''Removal of defective RBCs''''' | ||
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''Response to infection (viral,bacterial,fungal,parasitic'')<br />[[Mononucleosis]], [[AIDS]], [[viral hepatitis]]<br />subacute [[bacterial endocarditis]], bacterial [[septicemia]]<br /> splenic [[abscess]], [[typhoid fever]]<br />[[brucellosis]],[[ leptospirosis]], [[tuberculosis]]<br />[[histoplasmosis]]<br />[[malaria]], [[leishmaniasis]], [[trypanosomiasis]]<br />[[ehrlichiosis]]<br />''Disordered immunoregulation''<br />[[Rheumatoid arthritis]]<br />[[SLE]]<br />[[Serum sickness]]<br />[[Autoimmune hemolytic anemia]]<br />[[Idiopathic thrombocytopenic purpura|Immune thrombocytopenia]]<br />[[sarcoidosis]]<br />drug reactions<br />'''''Extramedullary hematopoiesis'''''<br />[[Myelofibrosis]]<br />Marrow infiltration by [[tumors]], [[leukemias]]<br />marrow damage by [[radiation]], [[toxins]] | ''Response to infection (viral,bacterial,fungal,parasitic'')<br />[[Mononucleosis]], [[AIDS]], [[viral hepatitis]]<br />subacute [[bacterial endocarditis]], bacterial [[septicemia]]<br /> splenic [[abscess]], [[typhoid fever]]<br />[[brucellosis]],[[ leptospirosis]], [[tuberculosis]]<br />[[histoplasmosis]]<br />[[malaria]], [[leishmaniasis]], [[trypanosomiasis]]<br />[[ehrlichiosis]]<br />''Disordered immunoregulation''<br />[[Rheumatoid arthritis]]<br />[[SLE]]<br />[[Serum sickness]]<br />[[Autoimmune hemolytic anemia]]<br />[[Idiopathic thrombocytopenic purpura|Immune thrombocytopenia]]<br />[[sarcoidosis]]<br />drug reactions<br />'''''Extramedullary hematopoiesis'''''<br />[[Myelofibrosis]]<br />Marrow infiltration by [[tumors]], [[leukemias]]<br />marrow damage by [[radiation]], [[toxins]] | ||
|'''''Organ Failure'''''<br /> | |'''''Organ Failure'''''<br /> | ||
[[Cirrhosis]]<br />[[congestive heart failure]]<br />'''''Vascular'''''<br />[[ | [[Cirrhosis]]<br />[[congestive heart failure]]<br />'''''Vascular'''''<br />[[Hepatic vein obstruction]]<br />[[Portal vein thrombosis|Portal vein obstruction]]<br />[[Budd-Chiari syndrome]]<br />[[Splenic vein obstruction]]<br />'''''Infections'''''<br /><br />Hepatic [[schistosomiasis]]<br />Hepatic [[echinococcosis]] | ||
|'''''Metabolic diseases'''''<br />[[Gauchers disease]]<br />[[Niemann-Pick disease]]<br />[[Hurler syndrome]] and other [[Mucopolysaccharidoses]]<br />[[Amyloidosis]]<br />[[Tangier disease]]<br />'''''Benign and malignant infiltrations'''''<br />[[Leukemias]](acute,chronic,lymphoid and myeloid)<br />lymphomas([[Hodgkins]] and [[Non-Hodgkin lymphoma|non-hodgkins]])<br />[[myeloproliferative]] disorders<br />[[metastatic]] tumors(commonly [[melanoma]])<br />[[histiocytosis X]]<br />[[Hemangioma]],[[lymphangioma]]<br />splenic [[cysts]]<br />[[hamartomas]]<br />[[eosinophilic granuloma]] | |'''''Metabolic diseases'''''<br />[[Gauchers disease]]<br />[[Niemann-Pick disease]]<br />[[Hurler syndrome]] and other [[Mucopolysaccharidoses]]<br />[[Amyloidosis]]<br />[[Tangier disease]]<br />'''''Benign and malignant infiltrations'''''<br />[[Leukemias]](acute,chronic,lymphoid and myeloid)<br />lymphomas([[Hodgkins]] and [[Non-Hodgkin lymphoma|non-hodgkins]])<br />[[myeloproliferative]] disorders<br />[[metastatic]] tumors(commonly [[melanoma]])<br />[[histiocytosis X]]<br />[[Hemangioma]],[[lymphangioma]]<br />splenic [[cysts]]<br />[[hamartomas]]<br />[[eosinophilic granuloma]] | ||
Revision as of 19:46, 21 May 2013
Template:Splenomegaly Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Causes
Causes in Alphabetical Order
Less common causes [3]
- Amyloidosis
- Babesiosis
- Gaucher's disease
- Histoplasmosis
- Kala-azar
- Rickets
- Schistosomiasis
- Syphilis
- Toxoplasmosis
- Typhoid fever
Causes by Organ System
Splenomegaly grouped on the basis of the pathogenic mechanism
Causes of Massive Splenomegaly (>1000gms)
- Autoimmune hemolytic anemia
- Chronic lymphocytic leukemia
- Chronic myelogenous leukemia
- Gauchers disease
- Hairy cell leukemia
- Kala-Azar (Leishmaniasis)
- Lymphomas
- Malaria
- Myelofibrosis
- Polycythemia vera
- Portal hypertension of Bilharziasis
- Sarcoidosis
- Thalassemia
References
- ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
- ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
- ↑ Kahan, Scott, Smith, Ellen G. In a page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:157