Alcoholic cardiomyopathy natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
In patients who continue to abuse alcohol, 4 year survival rate is 50%. On the contrary, abstinence is associated with regression of symptoms and overall improvement. Improvement in cardiac function evident from echocardiographic findings can also be noted. | In patients who continue to abuse alcohol, 4 year survival rate is 50%. On the contrary, abstinence is associated with regression of symptoms and overall improvement. Improvement in cardiac function evident from echocardiographic findings can also be noted. | ||
==Natural History== | ==Natural History, Complications and Prognosis== | ||
===Natural History=== | |||
Natural course of alcoholic cardiomyopathy depends on the ability of the patient to abstain from alcohol after being diagnosed. Many case reports and small studies have shown that abstinence from alcohol lead to marked improvement in the clinical condition of the patient. Similarly, conditions of a few patients worsened with continued alcohol intake.<ref name="pmid9164905">{{cite journal|author=Guillo P, Mansourati J, Maheu B, ''et al.'' |title=Long-term prognosis in patients with alcoholic cardiomyopathy and severe heart failure after total abstinence |journal=[[The American Journal of Cardiology]] |volume=79 |issue=9 |pages=1276–8 |year=1997 |month=May |pmid=9164905 |doi= |url=}}</ref><ref name="pmid2131353">{{cite journal |author=Masani F, Kato H, Sasagawa Y, ''et al.'' |title=[An echocardiographic study of alcoholic cardiomyopathy after total abstinence] |language=Japanese |journal=[[Journal of Cardiology]] |volume=20 |issue=3 |pages=627–34 |year=1990 |pmid=2131353 |doi= |url=}}</ref><ref name="pmid3530014">{{cite journal |author=Agatston AS, Snow ME, Samet P |title=Regression of severe alcoholic cardiomyopathy after abstinence of 10 weeks|journal=[[Alcoholism, Clinical and Experimental Research]] |volume=10 |issue=4 |pages=386–7 |year=1986 |month=August |pmid=3530014 |doi= |url=}}</ref><ref name="pmid2125195">{{cite journal |author=Mansourati J, Forneiro I, Genet L, Le Pichon J, Blanc JJ |title=[Regression of dilated cardiomyopathy in a chronic alcoholic patient after abstinence from alcohol] |language=French |journal=[[Archives Des Maladies Du Coeur Et Des Vaisseaux]] |volume=83 |issue=12|pages=1849–52; discussion 1853 |year=1990 |month=November |pmid=2125195 |doi= |url=}}</ref> Estruch et al found that a positive correlation exists between alcoholic cardiomyopathy and cirrhosis. The study stated that alcoholics who were hospitalized solely for cardiomyopathy had a higher prevalence of [[cirrhosis]] than those without heart disease.<ref name="pmid7635421">{{cite journal |author=Estruch R, Fernández-Solá J, Sacanella E, Paré C, Rubin E, Urbano-Márquez A |title=Relationship between cardiomyopathy and liver disease in chronic alcoholism |journal=[[Hepatology (Baltimore, Md.)]] |volume=22 |issue=2 |pages=532–8 |year=1995 |month=August |pmid=7635421 |doi= |url=}}</ref> | Natural course of alcoholic cardiomyopathy depends on the ability of the patient to abstain from alcohol after being diagnosed. Many case reports and small studies have shown that abstinence from alcohol lead to marked improvement in the clinical condition of the patient. Similarly, conditions of a few patients worsened with continued alcohol intake.<ref name="pmid9164905">{{cite journal|author=Guillo P, Mansourati J, Maheu B, ''et al.'' |title=Long-term prognosis in patients with alcoholic cardiomyopathy and severe heart failure after total abstinence |journal=[[The American Journal of Cardiology]] |volume=79 |issue=9 |pages=1276–8 |year=1997 |month=May |pmid=9164905 |doi= |url=}}</ref><ref name="pmid2131353">{{cite journal |author=Masani F, Kato H, Sasagawa Y, ''et al.'' |title=[An echocardiographic study of alcoholic cardiomyopathy after total abstinence] |language=Japanese |journal=[[Journal of Cardiology]] |volume=20 |issue=3 |pages=627–34 |year=1990 |pmid=2131353 |doi= |url=}}</ref><ref name="pmid3530014">{{cite journal |author=Agatston AS, Snow ME, Samet P |title=Regression of severe alcoholic cardiomyopathy after abstinence of 10 weeks|journal=[[Alcoholism, Clinical and Experimental Research]] |volume=10 |issue=4 |pages=386–7 |year=1986 |month=August |pmid=3530014 |doi= |url=}}</ref><ref name="pmid2125195">{{cite journal |author=Mansourati J, Forneiro I, Genet L, Le Pichon J, Blanc JJ |title=[Regression of dilated cardiomyopathy in a chronic alcoholic patient after abstinence from alcohol] |language=French |journal=[[Archives Des Maladies Du Coeur Et Des Vaisseaux]] |volume=83 |issue=12|pages=1849–52; discussion 1853 |year=1990 |month=November |pmid=2125195 |doi= |url=}}</ref> Estruch et al found that a positive correlation exists between alcoholic cardiomyopathy and cirrhosis. The study stated that alcoholics who were hospitalized solely for cardiomyopathy had a higher prevalence of [[cirrhosis]] than those without heart disease.<ref name="pmid7635421">{{cite journal |author=Estruch R, Fernández-Solá J, Sacanella E, Paré C, Rubin E, Urbano-Márquez A |title=Relationship between cardiomyopathy and liver disease in chronic alcoholism |journal=[[Hepatology (Baltimore, Md.)]] |volume=22 |issue=2 |pages=532–8 |year=1995 |month=August |pmid=7635421 |doi= |url=}}</ref> | ||
==Complications== | ===Complications=== | ||
Common cardiovascular complications of chronic alcohol abuse include: | Common cardiovascular complications of chronic alcohol abuse include: | ||
* [[Congestive heart failure]] | * [[Congestive heart failure]] | ||
| Line 17: | Line 18: | ||
* [[Sudden death]] | * [[Sudden death]] | ||
==Prognosis== | ===Prognosis=== | ||
Prognosis of alcoholic cardiomyopathy (AC) is worse compared with that of dilated cardiomyopathy. Studies have shown that abstinence results in improvement in clinical condition in AC. In patients who continue to abuse alcohol clinical condition is tend to get worsened, eventually leading to death due to heart failure. 4 year survival rate in patients who continue to consume alcohol is 50%. <ref name="pmid18034302">{{cite journal |author=Skotzko CE, Vrinceanu A, Krueger L, Freudenberger R |title=Alcohol use and congestive heart failure: incidence, importance, and approaches to improved history taking |journal=[[Heart Failure Reviews]] |volume=14 |issue=1 |pages=51–5 |year=2009 |month=March |pmid=18034302 |doi=10.1007/s10741-007-9048-8 |url=}}</ref> | Prognosis of alcoholic cardiomyopathy (AC) is worse compared with that of dilated cardiomyopathy. Studies have shown that abstinence results in improvement in clinical condition in AC. In patients who continue to abuse alcohol clinical condition is tend to get worsened, eventually leading to death due to heart failure. 4 year survival rate in patients who continue to consume alcohol is 50%. <ref name="pmid18034302">{{cite journal |author=Skotzko CE, Vrinceanu A, Krueger L, Freudenberger R |title=Alcohol use and congestive heart failure: incidence, importance, and approaches to improved history taking |journal=[[Heart Failure Reviews]] |volume=14 |issue=1 |pages=51–5 |year=2009 |month=March |pmid=18034302 |doi=10.1007/s10741-007-9048-8 |url=}}</ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Cardiology]] | [[Category:Cardiology]] | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Revision as of 12:47, 24 June 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]; Hardik Patel, M.D.
Overview
In patients who continue to abuse alcohol, 4 year survival rate is 50%. On the contrary, abstinence is associated with regression of symptoms and overall improvement. Improvement in cardiac function evident from echocardiographic findings can also be noted.
Natural History, Complications and Prognosis
Natural History
Natural course of alcoholic cardiomyopathy depends on the ability of the patient to abstain from alcohol after being diagnosed. Many case reports and small studies have shown that abstinence from alcohol lead to marked improvement in the clinical condition of the patient. Similarly, conditions of a few patients worsened with continued alcohol intake.[1][2][3][4] Estruch et al found that a positive correlation exists between alcoholic cardiomyopathy and cirrhosis. The study stated that alcoholics who were hospitalized solely for cardiomyopathy had a higher prevalence of cirrhosis than those without heart disease.[5]
Complications
Common cardiovascular complications of chronic alcohol abuse include:
- Congestive heart failure
- Arrhythmias (atrial fibrillation, atrial flutter, supraventricular tachycardias and premature ventricular complexes)
- Hypertension
- Stroke
- Sudden death
Prognosis
Prognosis of alcoholic cardiomyopathy (AC) is worse compared with that of dilated cardiomyopathy. Studies have shown that abstinence results in improvement in clinical condition in AC. In patients who continue to abuse alcohol clinical condition is tend to get worsened, eventually leading to death due to heart failure. 4 year survival rate in patients who continue to consume alcohol is 50%. [6]
References
- ↑ Guillo P, Mansourati J, Maheu B; et al. (1997). "Long-term prognosis in patients with alcoholic cardiomyopathy and severe heart failure after total abstinence". The American Journal of Cardiology. 79 (9): 1276–8. PMID 9164905. Unknown parameter
|month=ignored (help) - ↑ Masani F, Kato H, Sasagawa Y; et al. (1990). "[An echocardiographic study of alcoholic cardiomyopathy after total abstinence]". Journal of Cardiology (in Japanese). 20 (3): 627–34. PMID 2131353.
- ↑ Agatston AS, Snow ME, Samet P (1986). "Regression of severe alcoholic cardiomyopathy after abstinence of 10 weeks". Alcoholism, Clinical and Experimental Research. 10 (4): 386–7. PMID 3530014. Unknown parameter
|month=ignored (help) - ↑ Mansourati J, Forneiro I, Genet L, Le Pichon J, Blanc JJ (1990). "[Regression of dilated cardiomyopathy in a chronic alcoholic patient after abstinence from alcohol]". Archives Des Maladies Du Coeur Et Des Vaisseaux (in French). 83 (12): 1849–52, discussion 1853. PMID 2125195. Unknown parameter
|month=ignored (help) - ↑ Estruch R, Fernández-Solá J, Sacanella E, Paré C, Rubin E, Urbano-Márquez A (1995). "Relationship between cardiomyopathy and liver disease in chronic alcoholism". Hepatology (Baltimore, Md.). 22 (2): 532–8. PMID 7635421. Unknown parameter
|month=ignored (help) - ↑ Skotzko CE, Vrinceanu A, Krueger L, Freudenberger R (2009). "Alcohol use and congestive heart failure: incidence, importance, and approaches to improved history taking". Heart Failure Reviews. 14 (1): 51–5. doi:10.1007/s10741-007-9048-8. PMID 18034302. Unknown parameter
|month=ignored (help)