Elastase in blood serum: Difference between revisions
Jump to navigation
Jump to search
Gerald Chi (talk | contribs) |
Gerald Chi (talk | contribs) |
||
Line 59: | Line 59: | ||
* [[Antineutrophil cytoplasmic antibody-associated vasculitis]]<ref name="Haubitz-1997">{{Cite journal | last1 = Haubitz | first1 = M. | last2 = Schulzeck | first2 = P. | last3 = Schellong | first3 = S. | last4 = Schulze | first4 = M. | last5 = Koch | first5 = KM. | last6 = Brunkhorst | first6 = R. | title = Complexed plasma elastase as an in vivo marker for leukocyte activation in antineutrophil cytoplasmic antibody-associated vasculitis. | journal = Arthritis Rheum | volume = 40 | issue = 9 | pages = 1680-4 | month = Sep | year = 1997 | doi = 10.1002/1529-0131(199709)40:9lt;1680::AID-ART18gt;3.0.CO;2-Q | PMID = 9324023 }}</ref> | * [[Antineutrophil cytoplasmic antibody-associated vasculitis]]<ref name="Haubitz-1997">{{Cite journal | last1 = Haubitz | first1 = M. | last2 = Schulzeck | first2 = P. | last3 = Schellong | first3 = S. | last4 = Schulze | first4 = M. | last5 = Koch | first5 = KM. | last6 = Brunkhorst | first6 = R. | title = Complexed plasma elastase as an in vivo marker for leukocyte activation in antineutrophil cytoplasmic antibody-associated vasculitis. | journal = Arthritis Rheum | volume = 40 | issue = 9 | pages = 1680-4 | month = Sep | year = 1997 | doi = 10.1002/1529-0131(199709)40:9lt;1680::AID-ART18gt;3.0.CO;2-Q | PMID = 9324023 }}</ref> | ||
* [[Cystic fibrosis]]<ref name="Costello-1996">{{Cite journal | last1 = Costello | first1 = CM. | last2 = O'Connor | first2 = CM. | last3 = Finlay | first3 = GA. | last4 = Shiels | first4 = P. | last5 = FitzGerald | first5 = MX. | last6 = Hayes | first6 = JP. | title = Effect of nebulised recombinant DNase on neutrophil elastase load in cystic fibrosis. | journal = Thorax | volume = 51 | issue = 6 | pages = 619-23 | month = Jun | year = 1996 | doi = | PMID = 8693445 }}</ref> | * [[Cystic fibrosis]]<ref name="Costello-1996">{{Cite journal | last1 = Costello | first1 = CM. | last2 = O'Connor | first2 = CM. | last3 = Finlay | first3 = GA. | last4 = Shiels | first4 = P. | last5 = FitzGerald | first5 = MX. | last6 = Hayes | first6 = JP. | title = Effect of nebulised recombinant DNase on neutrophil elastase load in cystic fibrosis. | journal = Thorax | volume = 51 | issue = 6 | pages = 619-23 | month = Jun | year = 1996 | doi = | PMID = 8693445 }}</ref> | ||
* [[Cardiopulmonary bypass]]{{Cite journal | last1 = Tönz | first1 = M. | last2 = Mihaljevic | first2 = T. | last3 = von Segesser | first3 = LK. | last4 = Fehr | first4 = J. | last5 = Schmid | first5 = ER. | last6 = Turina | first6 = MI. | title = Acute lung injury during cardiopulmonary bypass. Are the neutrophils responsible? | journal = Chest | volume = 108 | issue = 6 | pages = 1551-6 | month = Dec | year = 1995 | doi = | PMID = 7497759 }} | * [[Cardiopulmonary bypass]]<ref>{{Cite journal | last1 = Tönz | first1 = M. | last2 = Mihaljevic | first2 = T. | last3 = von Segesser | first3 = LK. | last4 = Fehr | first4 = J. | last5 = Schmid | first5 = ER. | last6 = Turina | first6 = MI. | title = Acute lung injury during cardiopulmonary bypass. Are the neutrophils responsible? | journal = Chest | volume = 108 | issue = 6 | pages = 1551-6 | month = Dec | year = 1995 | doi = | PMID = 7497759 }}</ref> | ||
* [[Adult respiratory distress syndrome]]{{Cite journal | last1 = Donnelly | first1 = SC. | last2 = MacGregor | first2 = I. | last3 = Zamani | first3 = A. | last4 = Gordon | first4 = MW. | last5 = Robertson | first5 = CE. | last6 = Steedman | first6 = DJ. | last7 = Little | first7 = K. | last8 = Haslett | first8 = C. | title = Plasma elastase levels and the development of the adult respiratory distress syndrome. | journal = Am J Respir Crit Care Med | volume = 151 | issue = 5 | pages = 1428-33 | month = May | year = 1995 | doi = 10.1164/ajrccm.151.5.7735596 | PMID = 7735596 }} | * [[Adult respiratory distress syndrome]]<ref>{{Cite journal | last1 = Donnelly | first1 = SC. | last2 = MacGregor | first2 = I. | last3 = Zamani | first3 = A. | last4 = Gordon | first4 = MW. | last5 = Robertson | first5 = CE. | last6 = Steedman | first6 = DJ. | last7 = Little | first7 = K. | last8 = Haslett | first8 = C. | title = Plasma elastase levels and the development of the adult respiratory distress syndrome. | journal = Am J Respir Crit Care Med | volume = 151 | issue = 5 | pages = 1428-33 | month = May | year = 1995 | doi = 10.1164/ajrccm.151.5.7735596 | PMID = 7735596 }}</ref> | ||
* [[Hemodialysis]]{{Cite journal | last1 = Cheung | first1 = AK. | last2 = Faezi-Jenkin | first2 = B. | last3 = Leypoldt | first3 = JK. | title = Effect of thrombosis on complement activation and neutrophil degranulation during in vitro hemodialysis. | journal = J Am Soc Nephrol | volume = 5 | issue = 1 | pages = 110-5 | month = Jul | year = 1994 | doi = | PMID = 7948777 }} | * [[Hemodialysis]]<ref>{{Cite journal | last1 = Cheung | first1 = AK. | last2 = Faezi-Jenkin | first2 = B. | last3 = Leypoldt | first3 = JK. | title = Effect of thrombosis on complement activation and neutrophil degranulation during in vitro hemodialysis. | journal = J Am Soc Nephrol | volume = 5 | issue = 1 | pages = 110-5 | month = Jul | year = 1994 | doi = | PMID = 7948777 }}</ref> | ||
* [[Pancreatic cancer]]{{Cite journal | last1 = Ito | first1 = T. | last2 = Kimura | first2 = T. | last3 = Nawata | first3 = H. | title = Serum elastase 1 appears specific for cancer of the pancreatic head. | journal = Am J Gastroenterol | volume = 86 | issue = 12 | pages = 1778-83 | month = Dec | year = 1991 | doi = | PMID = 1962622 }} | * [[Pancreatic cancer]]<ref>{{Cite journal | last1 = Ito | first1 = T. | last2 = Kimura | first2 = T. | last3 = Nawata | first3 = H. | title = Serum elastase 1 appears specific for cancer of the pancreatic head. | journal = Am J Gastroenterol | volume = 86 | issue = 12 | pages = 1778-83 | month = Dec | year = 1991 | doi = | PMID = 1962622 }}</ref> | ||
* [[Coronary angioplasty]]{{Cite journal | last1 = De Servi | first1 = S. | last2 = Mazzone | first2 = A. | last3 = Ricevuti | first3 = G. | last4 = Fioravanti | first4 = A. | last5 = Bramucci | first5 = E. | last6 = Angoli | first6 = L. | last7 = Stefano | first7 = G. | last8 = Specchia | first8 = G. | title = Granulocyte activation after coronary angioplasty in humans. | journal = Circulation | volume = 82 | issue = 1 | pages = 140-6 | month = Jul | year = 1990 | doi = | PMID = 2163778 }} | * [[Coronary angioplasty]]<ref>{{Cite journal | last1 = De Servi | first1 = S. | last2 = Mazzone | first2 = A. | last3 = Ricevuti | first3 = G. | last4 = Fioravanti | first4 = A. | last5 = Bramucci | first5 = E. | last6 = Angoli | first6 = L. | last7 = Stefano | first7 = G. | last8 = Specchia | first8 = G. | title = Granulocyte activation after coronary angioplasty in humans. | journal = Circulation | volume = 82 | issue = 1 | pages = 140-6 | month = Jul | year = 1990 | doi = | PMID = 2163778 }}</ref> | ||
* Chronic joint disorders | * Chronic joint disorders |
Revision as of 01:45, 28 June 2013
Elastase in blood serum |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
- The presence of elastase in the blood serum is caused by serine proteinase hydrolyzing elastic occuring in the endothelial cells, macrophages, and granulocytes
Reference Range | |
In Plasma | 60-110 ng/ml |
In Pleural Effusion | 480-2900 ng/ml |
Causes of decreased elastase in blood serum
Causes of increased elastase in blood serum[3][4]
Common Causes
- Acute lung injury[5]
- Ischemia-reperfusion Injury[6]
- Neutrophilic asthma[7]
- Exercise[8][9]
- Celiac disease[10]
- Systolic hypertension[11]
- Endotoxemia[12][13]
- Diabetes mellitus[8]
- Carotid atherosclerotic plaque development[14]
- Oxidative stress[15]
- Essential thrombocythemia[16]
- Polycythemia vera[16]
- Extracorporeal detoxification[17]
- Esophagogastrectomy[18]
- Alpha1-antitrypsin deficiency[19]
- Migraine[20]
- Granulocyte colony-stimulating factor[21]
- Antineutrophil cytoplasmic antibody-associated vasculitis[22]
- Cystic fibrosis[23]
- Cardiopulmonary bypass[24]
- Adult respiratory distress syndrome[25]
- Hemodialysis[26]
- Pancreatic cancer[27]
- Coronary angioplasty[28]
- Chronic joint disorders
- Multiple trauma
- Sepsis
- Shock
- Shock lung in pre-eclampsia
Causes by Organ System
Cardiovascular | No underlying causes |
Chemical/Poisoning | No underlying causes |
Dental | No underlying causes |
Dermatologic | No underlying causes |
Drug Side Effect | No underlying causes |
Ear Nose Throat | No underlying causes |
Endocrine | No underlying causes |
Environmental | No underlying causes |
Gastroenterologic | No underlying causes |
Genetic | No underlying causes |
Hematologic | No underlying causes |
Iatrogenic | No underlying causes |
Infectious Disease | No underlying causes |
Musculoskeletal/Orthopedic | No underlying causes |
Neurologic | No underlying causes |
Nutritional/Metabolic | No underlying causes |
Obstetric/Gynecologic | No underlying causes |
Oncologic | No underlying causes |
Ophthalmologic | No underlying causes |
Overdose/Toxicity | No underlying causes |
Psychiatric | No underlying causes |
Pulmonary | No underlying causes |
Renal/Electrolyte | No underlying causes |
Rheumatology/Immunology/Allergy | No underlying causes |
Sexual | No underlying causes |
Trauma | No underlying causes |
Urologic | No underlying causes |
Miscellaneous | No underlying causes |
Causes in Alphabetical Order
References
- ↑ Stegenga, ME.; van der Crabben, SN.; Blümer, RM.; Levi, M.; Meijers, JC.; Serlie, MJ.; Tanck, MW.; Sauerwein, HP.; van der Poll, T. (2008). "Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia". Blood. 112 (1): 82–9. doi:10.1182/blood-2007-11-121723. PMID 18316629. Unknown parameter
|month=
ignored (help) - ↑ de Kruif, MD.; Lemaire, LC.; Giebelen, IA.; van Zoelen, MA.; Pater, JM.; van den Pangaart, PS.; Groot, AP.; de Vos, AF.; Elliott, PJ. (2007). "Prednisolone dose-dependently influences inflammation and coagulation during human endotoxemia". J Immunol. 178 (3): 1845–51. PMID 17237435. Unknown parameter
|month=
ignored (help) - ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
- ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
- ↑ Donnelly, SC.; MacGregor, I.; Zamani, A.; Gordon, MW.; Robertson, CE.; Steedman, DJ.; Little, K.; Haslett, C. (1995). "Plasma elastase levels and the development of the adult respiratory distress syndrome". Am J Respir Crit Care Med. 151 (5): 1428–33. doi:10.1164/ajrccm.151.5.7735596. PMID 7735596. Unknown parameter
|month=
ignored (help) - ↑ Hughes, SF.; Cotter, MJ.; Evans, SA.; Jones, KP.; Adams, RA. (2006). "Role of leucocytes in damage to the vascular endothelium during ischaemia-reperfusion injury". Br J Biomed Sci. 63 (4): 166–70. PMID 17201205.
- ↑ Baines, KJ.; Simpson, JL.; Wood, LG.; Scott, RJ.; Gibson, PG. (2011). "Systemic upregulation of neutrophil α-defensins and serine proteases in neutrophilic asthma". Thorax. 66 (11): 942–7. doi:10.1136/thx.2010.157719. PMID 21785157. Unknown parameter
|month=
ignored (help) - ↑ 8.0 8.1 Hu, H.; Johansson, BL.; Hjemdahl, P.; Li, N. (2004). "Exercise-induced platelet and leucocyte activation is not enhanced in well-controlled Type 1 diabetes, despite increased activity at rest". Diabetologia. 47 (5): 853–9. doi:10.1007/s00125-004-1378-7. PMID 15095037. Unknown parameter
|month=
ignored (help) - ↑ Li, N.; He, S.; Blombäck, M.; Hjemdahl, P. (2007). "Platelet activity, coagulation, and fibrinolysis during exercise in healthy males: effects of thrombin inhibition by argatroban and enoxaparin". Arterioscler Thromb Vasc Biol. 27 (2): 407–13. doi:10.1161/01.ATV.0000253906.19648.ac. PMID 17138937. Unknown parameter
|month=
ignored (help) - ↑ Carroccio, A.; Di Prima, L.; Scalici, C.; Soresi, M.; Cefalù, AB.; Noto, D.; Averna, MR.; Montalto, G.; Iacono, G. (2006). "Unexplained elevated serum pancreatic enzymes: a reason to suspect celiac disease". Clin Gastroenterol Hepatol. 4 (4): 455–9. doi:10.1016/j.cgh.2005.12.027. PMID 16616350. Unknown parameter
|month=
ignored (help) - ↑ Yasmin, CM.; McEniery, S.; Wallace, Z.; Dakham, P.; Pulsalkar, P.; Pusalkar, K.; Maki-Petaja, MJ.; Ashby, JR.; Cockcroft, IB. (2005). "Matrix metalloproteinase-9 (MMP-9), MMP-2, and serum elastase activity are associated with systolic hypertension and arterial stiffness". Arterioscler Thromb Vasc Biol. 25 (2): 372. doi:10.1161/01.ATV.0000151373.33830.41. PMID 15556929. Unknown parameter
|month=
ignored (help) - ↑ O'Brien, JM.; Abraham, E. (2004). "Human models of endotoxemia and recombinant human activated protein C.". Crit Care Med. 32 (5 Suppl): S202–8. PMID 15118518. Unknown parameter
|month=
ignored (help) - ↑ Pajkrt, D.; Camoglio, L.; Tiel-van Buul, MC.; de Bruin, K.; Cutler, DL.; Affrime, MB.; Rikken, G.; van der Poll, T.; ten Cate, JW. (1997). "Attenuation of proinflammatory response by recombinant human IL-10 in human endotoxemia: effect of timing of recombinant human IL-10 administration". J Immunol. 158 (8): 3971–7. PMID 9103468. Unknown parameter
|month=
ignored (help) - ↑ Zureik, M.; Robert, L.; Courbon, D.; Touboul, PJ.; Bizbiz, L.; Ducimetière, P. (2002). "Serum elastase activity, serum elastase inhibitors, and occurrence of carotid atherosclerotic plaques: the Etude sur le Vieillissement Artériel (EVA) study". Circulation. 105 (22): 2638–45. PMID 12045170. Unknown parameter
|month=
ignored (help) - ↑ Clermont, G.; Lecour, S.; Cabanne, JF.; Motte, G.; Guilland, JC.; Chevet, D.; Rochette, L. (2001). "Vitamin E-coated dialyzer reduces oxidative stress in hemodialysis patients". Free Radic Biol Med. 31 (2): 233–41. PMID 11440835. Unknown parameter
|month=
ignored (help) - ↑ 16.0 16.1 Falanga, A.; Marchetti, M.; Evangelista, V.; Vignoli, A.; Licini, M.; Balicco, M.; Manarini, S.; Finazzi, G.; Cerletti, C. (2000). "Polymorphonuclear leukocyte activation and hemostasis in patients with essential thrombocythemia and polycythemia vera". Blood. 96 (13): 4261–6. PMID 11110700. Unknown parameter
|month=
ignored (help) - ↑ Kramer, L.; Gendo, A.; Madl, C.; Ferrara, I.; Funk, G.; Schenk, P.; Sunder-Plassmann, G.; Hörl, WH. (2000). "Biocompatibility of a cuprophane charcoal-based detoxification device in cirrhotic patients with hepatic encephalopathy". Am J Kidney Dis. 36 (6): 1193–200. doi:10.1053/ajkd.2000.19834. PMID 11096044. Unknown parameter
|month=
ignored (help) - ↑ Reid, PT.; Donnelly, SC.; MacGregor, IR.; Grant, IS.; Cameron, E.; Walker, W.; Merrick, MV.; Haslett, C. (2000). "Pulmonary endothelial permeability and circulating neutrophil-endothelial markers in patients undergoing esophagogastrectomy". Crit Care Med. 28 (9): 3161–5. PMID 11008975. Unknown parameter
|month=
ignored (help) - ↑ Hill, AT.; Bayley, DL.; Campbell, EJ.; Hill, SL.; Stockley, RA. (2000). "Airways inflammation in chronic bronchitis: the effects of smoking and alpha1-antitrypsin deficiency". Eur Respir J. 15 (5): 886–90. PMID 10853853. Unknown parameter
|month=
ignored (help) - ↑ Tzourio, C.; El Amrani, M.; Robert, L.; Alpérovitch, A. (2000). "Serum elastase activity is elevated in migraine". Ann Neurol. 47 (5): 648–51. PMID 10805337. Unknown parameter
|month=
ignored (help) - ↑ Falanga, A.; Marchetti, M.; Evangelista, V.; Manarini, S.; Oldani, E.; Giovanelli, S.; Galbusera, M.; Cerletti, C.; Barbui, T. (1999). "Neutrophil activation and hemostatic changes in healthy donors receiving granulocyte colony-stimulating factor". Blood. 93 (8): 2506–14. PMID 10194429. Unknown parameter
|month=
ignored (help) - ↑ Haubitz, M.; Schulzeck, P.; Schellong, S.; Schulze, M.; Koch, KM.; Brunkhorst, R. (1997). "Complexed plasma elastase as an in vivo marker for leukocyte activation in antineutrophil cytoplasmic antibody-associated vasculitis". Arthritis Rheum. 40 (9): 1680–4. doi:10.1002/1529-0131(199709)40:9lt;1680::AID-ART18gt;3.0.CO;2-Q. PMID 9324023. Unknown parameter
|month=
ignored (help) - ↑ Costello, CM.; O'Connor, CM.; Finlay, GA.; Shiels, P.; FitzGerald, MX.; Hayes, JP. (1996). "Effect of nebulised recombinant DNase on neutrophil elastase load in cystic fibrosis". Thorax. 51 (6): 619–23. PMID 8693445. Unknown parameter
|month=
ignored (help) - ↑ Tönz, M.; Mihaljevic, T.; von Segesser, LK.; Fehr, J.; Schmid, ER.; Turina, MI. (1995). "Acute lung injury during cardiopulmonary bypass. Are the neutrophils responsible?". Chest. 108 (6): 1551–6. PMID 7497759. Unknown parameter
|month=
ignored (help) - ↑ Donnelly, SC.; MacGregor, I.; Zamani, A.; Gordon, MW.; Robertson, CE.; Steedman, DJ.; Little, K.; Haslett, C. (1995). "Plasma elastase levels and the development of the adult respiratory distress syndrome". Am J Respir Crit Care Med. 151 (5): 1428–33. doi:10.1164/ajrccm.151.5.7735596. PMID 7735596. Unknown parameter
|month=
ignored (help) - ↑ Cheung, AK.; Faezi-Jenkin, B.; Leypoldt, JK. (1994). "Effect of thrombosis on complement activation and neutrophil degranulation during in vitro hemodialysis". J Am Soc Nephrol. 5 (1): 110–5. PMID 7948777. Unknown parameter
|month=
ignored (help) - ↑ Ito, T.; Kimura, T.; Nawata, H. (1991). "Serum elastase 1 appears specific for cancer of the pancreatic head". Am J Gastroenterol. 86 (12): 1778–83. PMID 1962622. Unknown parameter
|month=
ignored (help) - ↑ De Servi, S.; Mazzone, A.; Ricevuti, G.; Fioravanti, A.; Bramucci, E.; Angoli, L.; Stefano, G.; Specchia, G. (1990). "Granulocyte activation after coronary angioplasty in humans". Circulation. 82 (1): 140–6. PMID 2163778. Unknown parameter
|month=
ignored (help)