Warty dyskeratoma: Difference between revisions
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==Overview== | ==Overview== | ||
Warty dyskeratoma, is a [[benign]]<ref name="pmid">{{cite journal |author=Diallo M, Cribier B, Scrivener Y |title=[Warty dyskeratoma: infundibular histogenesis. Anatomoclinical study of 43 cases] |language=French |journal=[[Ann Dermatol Venereol]] |volume=134 |issue=8-9 |pages=633–6 |year=2007 |pmid= 17925685|doi= |url=http://www.masson.fr/masson/MDOI-AD-08-2007-134-8-0151-9638-101019-200520001 |issn=}}</ref> [[epidermis (skin)|epidermal]] proliferation with distinctive histologic findings that may mimic invasive squamous cell carcinoma<ref name="pmid6434720">{{cite journal |author=Chau MN, Radden BG |title=Oral warty dyskeratoma |journal=[[J. Oral Pathol.]] |volume=13 |issue=5 |pages=546–56 |year=1984 |month=October |pmid=6434720 |doi= 10.1111/j.1600-0714.1984.tb01455.x|url= |issn=}}</ref> and commonly manifests as an umbilicated (Having a central mark or depression resembling a [[navel]]) lesion with a [[keratotic plug]],<ref name="pmid6698687">{{cite journal |author=Kaugars GE, Lieb RJ, Abbey LM |title=Focal oral warty dyskeratoma |journal=[[Int. J. Dermatol.]] |volume=23 |issue=2 |pages=123–30 |year=1984 |month=March |pmid=6698687 |doi= 10.1111/j.1365-4362.1984.tb05686.x|url= |issn=}}</ref> WD have some histopathologic similarities to [[viral warts]] but it's not caused by [[HPV]] and the majority of these lesions display overall histopathologic features consistent with a [[follicular adnexal neoplasm]].<ref name="pmid12196754">{{cite journal |author=Kaddu S, Dong H, Mayer G, Kerl H, Cerroni L |title=Warty dyskeratoma--"follicular dyskeratoma": analysis of clinicopathologic features of a distinctive follicular adnexal neoplasm |journal=[[J. Am. Acad. Dermatol.]] |volume=47 |issue=3 |pages=423–8 |year=2002 |month=September |pmid=12196754 |doi= 10.1067/mjd.2002.122756|url=http://linkinghub.elsevier.com/retrieve/pii/S0190962202001317 |issn=}}</ref> usually limited to the [[head]], [[neck]],<ref name="pmid6642851">{{cite journal |author=Duray PH, Merino MJ, Axiotis C |title=Warty dyskeratoma of the vulva |journal=[[Int. J. Gynecol. Pathol.]] |volume=2 |issue=3 |pages=286–93 |year=1983 |pmid=6642851 |doi= 10.1097/00004347-198303000-00006|url= |issn=}}</ref> [[scalp]]<ref name="pmid9499610">{{cite journal |author=Griffiths TW, Hashimoto K, Sharata HH, Ellis CN |title=Multiple warty dyskeratomas of the scalp |journal=[[Clin. Exp. Dermatol.]] |volume=22 |issue=4 |pages=189–91 |year=1997 |month=July |pmid=9499610 |doi= 10.1111/j.1365-2230.1997.tb01059.x|url= |issn=}}</ref> or [[face]] and [[vulva]].<ref name="pmid6642851"/> Lesions are generally [[wikt:solitary|solitary]] and sporadic and may be associated with a [[follicular unit]]. [[Mouth|Oral]] involvement,<ref name="pmid6698687"/> particularly the [[hard palate]], and [[genital]] involvement have been reported. it can also be thought of as one of the manifestations of focal [[acantholytic]] [[dyskeratosis]], an epidermal reaction pattern that can be seen in several disorders, including [[Darier's disease]] and [[Grover's disease]].<ref name="Andrews">{{cite book |author=James, William D.; Berger, Timothy G.; et al. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |location= |year=2006 |pages= |isbn=0-7216-2921-0 |oclc= |doi= |accessdate=}}</ref> | Warty dyskeratoma, is a [[benign]]<ref name="pmid">{{cite journal |author=Diallo M, Cribier B, Scrivener Y |title=[Warty dyskeratoma: infundibular histogenesis. Anatomoclinical study of 43 cases] |language=French |journal=[[Ann Dermatol Venereol]] |volume=134 |issue=8-9 |pages=633–6 |year=2007 |pmid= 17925685|doi= |url=http://www.masson.fr/masson/MDOI-AD-08-2007-134-8-0151-9638-101019-200520001 |issn=}}</ref> [[epidermis (skin)|epidermal]] proliferation with distinctive histologic findings that may mimic invasive squamous cell carcinoma<ref name="pmid6434720">{{cite journal |author=Chau MN, Radden BG |title=Oral warty dyskeratoma |journal=[[J. Oral Pathol.]] |volume=13 |issue=5 |pages=546–56 |year=1984 |month=October |pmid=6434720 |doi= 10.1111/j.1600-0714.1984.tb01455.x|url= |issn=}}</ref> and commonly manifests as an umbilicated (Having a central mark or depression resembling a [[navel]]) lesion with a [[keratotic plug]],<ref name="pmid6698687">{{cite journal |author=Kaugars GE, Lieb RJ, Abbey LM |title=Focal oral warty dyskeratoma |journal=[[Int. J. Dermatol.]] |volume=23 |issue=2 |pages=123–30 |year=1984 |month=March |pmid=6698687 |doi= 10.1111/j.1365-4362.1984.tb05686.x|url= |issn=}}</ref> WD have some histopathologic similarities to [[viral warts]] but it's not caused by [[HPV]] and the majority of these lesions display overall histopathologic features consistent with a [[follicular adnexal neoplasm]].<ref name="pmid12196754">{{cite journal |author=Kaddu S, Dong H, Mayer G, Kerl H, Cerroni L |title=Warty dyskeratoma--"follicular dyskeratoma": analysis of clinicopathologic features of a distinctive follicular adnexal neoplasm |journal=[[J. Am. Acad. Dermatol.]] |volume=47 |issue=3 |pages=423–8 |year=2002 |month=September |pmid=12196754 |doi= 10.1067/mjd.2002.122756|url=http://linkinghub.elsevier.com/retrieve/pii/S0190962202001317 |issn=}}</ref> usually limited to the [[head]], [[neck]],<ref name="pmid6642851">{{cite journal |author=Duray PH, Merino MJ, Axiotis C |title=Warty dyskeratoma of the vulva |journal=[[Int. J. Gynecol. Pathol.]] |volume=2 |issue=3 |pages=286–93 |year=1983 |pmid=6642851 |doi= 10.1097/00004347-198303000-00006|url= |issn=}}</ref> [[scalp]]<ref name="pmid9499610">{{cite journal |author=Griffiths TW, Hashimoto K, Sharata HH, Ellis CN |title=Multiple warty dyskeratomas of the scalp |journal=[[Clin. Exp. Dermatol.]] |volume=22 |issue=4 |pages=189–91 |year=1997 |month=July |pmid=9499610 |doi= 10.1111/j.1365-2230.1997.tb01059.x|url= |issn=}}</ref> or [[face]] and [[vulva]].<ref name="pmid6642851"/> Lesions are generally [[wikt:solitary|solitary]] and sporadic and may be associated with a [[follicular unit]]. [[Mouth|Oral]] involvement,<ref name="pmid6698687"/> particularly the [[hard palate]], and [[genital]] involvement have been reported. it can also be thought of as one of the manifestations of focal [[acantholytic]] [[dyskeratosis]], an epidermal reaction pattern that can be seen in several disorders, including [[Darier's disease]] and [[Grover's disease]].<ref name="Andrews">{{cite book |author=James, William D.; Berger, Timothy G.; et al. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |location= |year=2006 |pages= |isbn=0-7216-2921-0 |oclc= |doi= |accessdate=}}</ref> But the main Difference between Darier disease and Warty dyskeratoma, is that Darier disease inherited [[dermatosis]] ([[autosomal dominant]]) consisting of multiple [[keratotic]] [[papules]] on the [[face]], [[torso|trunk]], and [[Limb (anatomy)|extremities]], while WD occurs as an isolated, noninherited, single keratotic nodule mainly confined to the [[head]] and [[neck]] as mentioned earlier.<ref name="pmid6642851"/> | ||
== Differential Diagnosis == | == Differential Diagnosis == | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: Isolated dyskeratosis follicularis
Overview
Warty dyskeratoma, is a benign[1] epidermal proliferation with distinctive histologic findings that may mimic invasive squamous cell carcinoma[2] and commonly manifests as an umbilicated (Having a central mark or depression resembling a navel) lesion with a keratotic plug,[3] WD have some histopathologic similarities to viral warts but it's not caused by HPV and the majority of these lesions display overall histopathologic features consistent with a follicular adnexal neoplasm.[4] usually limited to the head, neck,[5] scalp[6] or face and vulva.[5] Lesions are generally solitary and sporadic and may be associated with a follicular unit. Oral involvement,[3] particularly the hard palate, and genital involvement have been reported. it can also be thought of as one of the manifestations of focal acantholytic dyskeratosis, an epidermal reaction pattern that can be seen in several disorders, including Darier's disease and Grover's disease.[7] But the main Difference between Darier disease and Warty dyskeratoma, is that Darier disease inherited dermatosis (autosomal dominant) consisting of multiple keratotic papules on the face, trunk, and extremities, while WD occurs as an isolated, noninherited, single keratotic nodule mainly confined to the head and neck as mentioned earlier.[5]
Differential Diagnosis
References
- ↑ Diallo M, Cribier B, Scrivener Y (2007). "[Warty dyskeratoma: infundibular histogenesis. Anatomoclinical study of 43 cases]". Ann Dermatol Venereol (in French). 134 (8–9): 633–6. PMID 17925685.
- ↑ Chau MN, Radden BG (1984). "Oral warty dyskeratoma". J. Oral Pathol. 13 (5): 546–56. doi:10.1111/j.1600-0714.1984.tb01455.x. PMID 6434720. Unknown parameter
|month=ignored (help) - ↑ 3.0 3.1 Kaugars GE, Lieb RJ, Abbey LM (1984). "Focal oral warty dyskeratoma". Int. J. Dermatol. 23 (2): 123–30. doi:10.1111/j.1365-4362.1984.tb05686.x. PMID 6698687. Unknown parameter
|month=ignored (help) - ↑ Kaddu S, Dong H, Mayer G, Kerl H, Cerroni L (2002). "Warty dyskeratoma--"follicular dyskeratoma": analysis of clinicopathologic features of a distinctive follicular adnexal neoplasm". J. Am. Acad. Dermatol. 47 (3): 423–8. doi:10.1067/mjd.2002.122756. PMID 12196754. Unknown parameter
|month=ignored (help) - ↑ 5.0 5.1 5.2 5.3 Duray PH, Merino MJ, Axiotis C (1983). "Warty dyskeratoma of the vulva". Int. J. Gynecol. Pathol. 2 (3): 286–93. doi:10.1097/00004347-198303000-00006. PMID 6642851.
- ↑ Griffiths TW, Hashimoto K, Sharata HH, Ellis CN (1997). "Multiple warty dyskeratomas of the scalp". Clin. Exp. Dermatol. 22 (4): 189–91. doi:10.1111/j.1365-2230.1997.tb01059.x. PMID 9499610. Unknown parameter
|month=ignored (help) - ↑ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.