Linear atrophoderma of Moulin: Difference between revisions
Jump to navigation
Jump to search
Rim Halaby (talk | contribs) No edit summary |
No edit summary |
||
Line 8: | Line 8: | ||
==Overview== | ==Overview== | ||
Linear atrophoderma of Moulin (LAM) is an acquired unilateral [[dermatitis]] localized along the [[Blaschko's lines]]. | Linear atrophoderma of Moulin (LAM) is an acquired unilateral [[hyperpigmented]] [[dermatitis]] localized along the [[Blaschko's lines]]. | ||
==Historical Perspective== | ==Historical Perspective== | ||
Line 15: | Line 15: | ||
==Pathophysiology== | ==Pathophysiology== | ||
LAM is a [[cutaneous]] form of [[mosaicism]] <ref name="pmid12963915">{{cite journal | author = Danarti R, Bittar M, Happle R, König A | title = Linear atrophoderma of Moulin: postulation of mosaicism for a predisposing gene | journal = [[Journal of the American Academy of Dermatology]] | volume = 49 | issue = 3 | pages = 492–8 | year = 2003 | month = September | pmid = 12963915 | doi = 10.1067/S0190-9622(03)00895-8| url = http://linkinghub.elsevier.com/retrieve/pii/S0190962203008958 | issn = }}</ref> | LAM is a [[cutaneous]] form of [[mosaicism]] <ref name="pmid12963915">{{cite journal | author = Danarti R, Bittar M, Happle R, König A | title = Linear atrophoderma of Moulin: postulation of mosaicism for a predisposing gene | journal = [[Journal of the American Academy of Dermatology]] | volume = 49 | issue = 3 | pages = 492–8 | year = 2003 | month = September | pmid = 12963915 | doi = 10.1067/S0190-9622(03)00895-8| url = http://linkinghub.elsevier.com/retrieve/pii/S0190962203008958 | issn = }}</ref> | ||
==Differential Diagnosis== | |||
The LAM must be distinguished from other [[linear dermatoses]]: | |||
*[[Blaschkitis acuta]] | |||
*[[Epidermal naevi]] | |||
*[[Inflammatory linear verrucous epidermal naevus]] | |||
*[[Lichen striatus]] | |||
*[[Linear lupus erythematosus]] | |||
*[[Linear scleroderma]] | |||
*[[Reticulate hyperpigmentation of Iijima]] | |||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
Only a few dozen cases of LAM have been described.<ref name="pmid16207193">{{cite journal | author = Miteva L, Nikolova K, Obreshkova E | title = Linear atrophoderma of Moulin | journal = [[International Journal of Dermatology]] | volume = 44 | issue = 10 | pages = 867–9 | year = 2005 | month = October | pmid = 16207193 | doi = 10.1111/j.1365-4632.2004.02221.x | url = http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0011-9059&date=2005&volume=44&issue=10&spage=867 | issn = }}</ref><ref name="pmid18086596">{{cite journal | author = Zampetti A, Antuzzi D, Caldarola G, Celleno L, Amerio P, Feliciani C | title = Linear atrophoderma of Moulin | journal = [[European Journal of Dermatology]] | volume = 18 | issue = 1 | pages = 79–80 | year = 2008 | pmid = 18086596 | doi = 10.1684/ejd.2007.0316 | url = http://www.john-libbey-eurotext.fr/medline.md?issn=1167-1122&vol=18&iss=1&page=79 | issn = }}</ref><ref name="pmid18713593">{{cite journal | author = Cecchi R, Bartoli L, Brunetti L, Pavesi M | title = Linear atrophoderma of Moulin localized to the neck | journal = [[Dermatology Online Journal]] | volume = 14 | issue = 6 | pages = 12 | year = 2008 | pmid = 18713593 | doi = | url = | issn = }}</ref> LAM affects [[children]] or [[adolescents]] of both genders. | Only a few dozen cases of LAM have been described.<ref name="pmid16207193">{{cite journal | author = Miteva L, Nikolova K, Obreshkova E | title = Linear atrophoderma of Moulin | journal = [[International Journal of Dermatology]] | volume = 44 | issue = 10 | pages = 867–9 | year = 2005 | month = October | pmid = 16207193 | doi = 10.1111/j.1365-4632.2004.02221.x | url = http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0011-9059&date=2005&volume=44&issue=10&spage=867 | issn = }}</ref><ref name="pmid18086596">{{cite journal | author = Zampetti A, Antuzzi D, Caldarola G, Celleno L, Amerio P, Feliciani C | title = Linear atrophoderma of Moulin | journal = [[European Journal of Dermatology]] | volume = 18 | issue = 1 | pages = 79–80 | year = 2008 | pmid = 18086596 | doi = 10.1684/ejd.2007.0316 | url = http://www.john-libbey-eurotext.fr/medline.md?issn=1167-1122&vol=18&iss=1&page=79 | issn = }}</ref><ref name="pmid18713593">{{cite journal | author = Cecchi R, Bartoli L, Brunetti L, Pavesi M | title = Linear atrophoderma of Moulin localized to the neck | journal = [[Dermatology Online Journal]] | volume = 14 | issue = 6 | pages = 12 | year = 2008 | pmid = 18713593 | doi = | url = | issn = }}</ref> LAM affects [[children]] or [[adolescents]] of both genders. | ||
==Complications, Natural History, Prognosis== | |||
===Prognosis=== | |||
The prognosis is good. | |||
==Diagnosis== | ==Diagnosis== | ||
Line 24: | Line 42: | ||
*The rash generally involves the trunk and limbs. | *The rash generally involves the trunk and limbs. | ||
without preceding inflammation, subsequent induration or scleroderma. Diagnosis is made clinically and histologically. We report a 22-year-old woman with a 17 year history of linear atrophoderma which involved the right arm and trunk. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} |
Revision as of 20:14, 29 July 2013
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: Moulin atrophoderma linearis, LAM
Overview
Linear atrophoderma of Moulin (LAM) is an acquired unilateral hyperpigmented dermatitis localized along the Blaschko's lines.
Historical Perspective
This disease was first referred to as Atrophoderma of Moulin after Dr.Moulin who first reported it in 1992[1] then was renamed as linear atrophoderma of Moulin.[2]
Pathophysiology
LAM is a cutaneous form of mosaicism [3]
Differential Diagnosis
The LAM must be distinguished from other linear dermatoses:
- Blaschkitis acuta
- Epidermal naevi
- Inflammatory linear verrucous epidermal naevus
- Lichen striatus
- Linear lupus erythematosus
- Linear scleroderma
- Reticulate hyperpigmentation of Iijima
Epidemiology and Demographics
Only a few dozen cases of LAM have been described.[4][5][6] LAM affects children or adolescents of both genders.
Complications, Natural History, Prognosis
Prognosis
The prognosis is good.
Diagnosis
Physcial Examination
Skin
- The rash generally involves the trunk and limbs.
without preceding inflammation, subsequent induration or scleroderma. Diagnosis is made clinically and histologically. We report a 22-year-old woman with a 17 year history of linear atrophoderma which involved the right arm and trunk.
References
- ↑ Moulin G, Hill MP, Guillaud V, Barrut D, Chevallier J, Thomas L (1992). "[Acquired atrophic pigmented band-like lesions following Blaschko's lines]". Annales de dermatologie et de vénéréologie (in French). 119 (10): 729–36. PMID 1296472.
- ↑ Baumann L, Happle R, Plewig G, Schirren CG (1994). "[Atrophodermia linearis Moulin. A new disease picture, following the Blaschko lines]". Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, Und Verwandte Gebiete (in German). 45 (4): 231–6. PMID 8014049. Unknown parameter
|month=
ignored (help) - ↑ Danarti R, Bittar M, Happle R, König A (2003). "Linear atrophoderma of Moulin: postulation of mosaicism for a predisposing gene". Journal of the American Academy of Dermatology. 49 (3): 492–8. doi:10.1067/S0190-9622(03)00895-8. PMID 12963915. Unknown parameter
|month=
ignored (help) - ↑ Miteva L, Nikolova K, Obreshkova E (2005). "Linear atrophoderma of Moulin". International Journal of Dermatology. 44 (10): 867–9. doi:10.1111/j.1365-4632.2004.02221.x. PMID 16207193. Unknown parameter
|month=
ignored (help) - ↑ Zampetti A, Antuzzi D, Caldarola G, Celleno L, Amerio P, Feliciani C (2008). "Linear atrophoderma of Moulin". European Journal of Dermatology. 18 (1): 79–80. doi:10.1684/ejd.2007.0316. PMID 18086596.
- ↑ Cecchi R, Bartoli L, Brunetti L, Pavesi M (2008). "Linear atrophoderma of Moulin localized to the neck". Dermatology Online Journal. 14 (6): 12. PMID 18713593.