Pseudoxanthoma elasticum epidemiology and demographics: Difference between revisions
No edit summary |
No edit summary |
||
| Line 7: | Line 7: | ||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
PXE is a rare disease but the exact prevalence is unknown. The prevalence has been suggested to be approximately 1:50,000,<ref name="Uitto-2012">{{Cite journal | last1 = Uitto | first1 = J. | title = Rare heritable skin diseases: targets for regenerative medicine. | journal = J Invest Dermatol | volume = 132 | issue = 11 | pages = 2485-8 | month = Nov | year = 2012 | doi = 10.1038/jid.2012.334 | PMID = 23069901 }}</ref> with an estimate of 150,000 affected in the world assuming the same global prevalence.<ref name="Uitto-2012">{{Cite journal | last1 = Uitto | first1 = J. | title = Rare heritable skin diseases: targets for regenerative medicine. | journal = J Invest Dermatol | volume = 132 | issue = 11 | pages = 2485-8 | month = Nov | year = 2012 | doi = 10.1038/jid.2012.334 | PMID = 23069901 }}</ref> Females are twice as likely to be affected as males. The disease occurs in all ethnicities, but South Africans are more likely to have PXE as a result of a [[founder effect]] (i.e. it was relatively prevalent in the small group of people from whom most South Africans descend).<ref name="Allen-1992">{{Cite journal | last1 = Allen | first1 = P. | last2 = Wightman | first2 = F. | title = Spectral pattern discrimination by children. | journal = J Speech Hear Res | volume = 35 | issue = 1 | pages = 222-33 | month = Feb | year = 1992 | doi = | PMID = 1735972 }}</ref> | PXE is a rare disease but the exact prevalence is unknown. The prevalence has been suggested to be approximately 1:50,000,<ref name="Uitto-2012">{{Cite journal | last1 = Uitto | first1 = J. | title = Rare heritable skin diseases: targets for regenerative medicine. | journal = J Invest Dermatol | volume = 132 | issue = 11 | pages = 2485-8 | month = Nov | year = 2012 | doi = 10.1038/jid.2012.334 | PMID = 23069901 }}</ref> with an estimate of 150,000 affected in the world assuming the same global prevalence.<ref name="Uitto-2012">{{Cite journal | last1 = Uitto | first1 = J. | title = Rare heritable skin diseases: targets for regenerative medicine. | journal = J Invest Dermatol | volume = 132 | issue = 11 | pages = 2485-8 | month = Nov | year = 2012 | doi = 10.1038/jid.2012.334 | PMID = 23069901 }}</ref> Females are twice as likely to be affected as males, and the average age of onset is 13 years. The disease occurs in all ethnicities, but South Africans are more likely to have PXE as a result of a [[founder effect]] (i.e. it was relatively prevalent in the small group of people from whom most South Africans descend).<ref name="Allen-1992">{{Cite journal | last1 = Allen | first1 = P. | last2 = Wightman | first2 = F. | title = Spectral pattern discrimination by children. | journal = J Speech Hear Res | volume = 35 | issue = 1 | pages = 222-33 | month = Feb | year = 1992 | doi = | PMID = 1735972 }}</ref> | ||
==References== | ==References== | ||
Revision as of 02:37, 19 August 2013
|
Pseudoxanthoma elasticum Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Pseudoxanthoma elasticum epidemiology and demographics On the Web |
|
American Roentgen Ray Society Images of Pseudoxanthoma elasticum epidemiology and demographics |
|
FDA on Pseudoxanthoma elasticum epidemiology and demographics |
|
Pseudoxanthoma elasticum epidemiology and demographics in the news |
|
Blogs on Pseudoxanthoma elasticum epidemiology and demographics |
|
Risk calculators and risk factors for Pseudoxanthoma elasticum epidemiology and demographics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ayokunle Olubaniyi, M.B,B.S [2]
Overview
Epidemiology and Demographics
PXE is a rare disease but the exact prevalence is unknown. The prevalence has been suggested to be approximately 1:50,000,[1] with an estimate of 150,000 affected in the world assuming the same global prevalence.[1] Females are twice as likely to be affected as males, and the average age of onset is 13 years. The disease occurs in all ethnicities, but South Africans are more likely to have PXE as a result of a founder effect (i.e. it was relatively prevalent in the small group of people from whom most South Africans descend).[2]
References
- ↑ 1.0 1.1 Uitto, J. (2012). "Rare heritable skin diseases: targets for regenerative medicine". J Invest Dermatol. 132 (11): 2485–8. doi:10.1038/jid.2012.334. PMID 23069901. Unknown parameter
|month=ignored (help) - ↑ Allen, P.; Wightman, F. (1992). "Spectral pattern discrimination by children". J Speech Hear Res. 35 (1): 222–33. PMID 1735972. Unknown parameter
|month=ignored (help)