Bezold-Jarisch reflex overview: Difference between revisions
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==Overview== | ==Overview== | ||
Bezold-Jarisch reflex is the occurrence of [[bradycardia]] and [[hypotension]] through a pathway involving cardiac receptors,[[medulla|medullary centers]] and [[vagus|vagal]] afferent nerves.<ref name="pmid11458703">{{cite journal| author=Aviado DM, Guevara Aviado D| title=The Bezold-Jarisch reflex. A historical perspective of cardiopulmonary reflexes. | journal=Ann N Y Acad Sci | year= 2001 | volume= 940 | issue= | pages= 48-58 | pmid=11458703 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11458703 }} </ref> It results from cardiovascular depressor reflex involving a marked increase in [[vagal]] efferent discharge to the heart, elicited by stimulation of [[mechanoreceptor]]s, primarily in the[[left ventricle]]. This leads to [[bradycardia]] and dilatation of the peripheral blood vessels with resulting lowering of the [[blood pressure]]. <ref> A. von Bezold, Ludwig Hirt (1844-1907): Über die physiologischen Wirkungen des essigsauren Veratrine. Untersuchungen aus dem Physiologischen Laboratorium in Würzburg, 1867, 1: 73-122.</ref> <ref>A. Jarisch, C. Henze Über Blutdrucksenkung durch chemische Erregung depressorischer Nerven. Naunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1937, 187: 706-730.</ref> <ref>A. Jarisch Vom Herzen ausgehende Kreislaufreflexe. Archiv für Kreislaufforschung 1940, 7: 260-274.</ref> Bezold-Jarisch reflex is responsible for 61% of [[bradyarrhythmia]] that occur within the first 60 minutes of inferoposterior [[myocardial infarction]].<ref>{{cite book|last=Goldman|first=Lee|title=Goldman: Goldman's Cecil Medicine|publisher=Saunders, an imprint of Elsevier Inc.|isbn=978-1-4377-1604-7|author2=Anderson, Jeffrey L.|edition=24th|chapter=ST SEGMENT ELEVATION ACUTE MYOCARDIAL INFARCTION AND COMPLICATIONS OF MYOCARDIAL INFARCTION|page=444}}</ref> In addition, it is considered a good prognostic indicator of successful early [[reperfusion]] and [[coronary artery]] patency in the setting of [[thrombolysis]] after inferoposterior [[MI]]. | Bezold-Jarisch reflex is the occurrence of [[bradycardia]] and [[hypotension]] through a pathway involving cardiac receptors,[[medulla|medullary centers]] and [[vagus|vagal]] afferent nerves.<ref name="pmid11458703">{{cite journal| author=Aviado DM, Guevara Aviado D| title=The Bezold-Jarisch reflex. A historical perspective of cardiopulmonary reflexes. | journal=Ann N Y Acad Sci | year= 2001 | volume= 940 | issue= | pages= 48-58 | pmid=11458703 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11458703 }} </ref> It results from cardiovascular depressor reflex involving a marked increase in [[vagal]] efferent discharge to the heart, elicited by stimulation of [[mechanoreceptor]]s, primarily in the[[left ventricle]]. This leads to [[bradycardia]] and dilatation of the peripheral blood vessels with resulting lowering of the [[blood pressure]]. <ref> A. von Bezold, Ludwig Hirt (1844-1907): Über die physiologischen Wirkungen des essigsauren Veratrine. Untersuchungen aus dem Physiologischen Laboratorium in Würzburg, 1867, 1: 73-122.</ref> <ref>A. Jarisch, C. Henze Über Blutdrucksenkung durch chemische Erregung depressorischer Nerven. Naunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1937, 187: 706-730.</ref> <ref>A. Jarisch Vom Herzen ausgehende Kreislaufreflexe. Archiv für Kreislaufforschung 1940, 7: 260-274.</ref> Bezold-Jarisch reflex is responsible for 61% of [[bradyarrhythmia]] that occur within the first 60 minutes of inferoposterior [[myocardial infarction]].<ref>{{cite book|last=Goldman|first=Lee|title=Goldman: Goldman's Cecil Medicine|publisher=Saunders, an imprint of Elsevier Inc.|isbn=978-1-4377-1604-7|author2=Anderson, Jeffrey L.|edition=24th|chapter=ST SEGMENT ELEVATION ACUTE MYOCARDIAL INFARCTION AND COMPLICATIONS OF MYOCARDIAL INFARCTION|page=444}}</ref> In addition, it is considered a good prognostic indicator of successful early [[reperfusion]] and [[coronary artery]] patency in the setting of [[thrombolysis]] after inferoposterior [[MI]]. | ||
==References== | ==References== |
Revision as of 16:52, 28 August 2013
Template:Bezold-Jarisch reflex
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Rim Halaby, M.D. [3]; Mugilan Poongkunran M.B.B.S [4]
Overview
Bezold-Jarisch reflex is the occurrence of bradycardia and hypotension through a pathway involving cardiac receptors,medullary centers and vagal afferent nerves.[1] It results from cardiovascular depressor reflex involving a marked increase in vagal efferent discharge to the heart, elicited by stimulation of mechanoreceptors, primarily in theleft ventricle. This leads to bradycardia and dilatation of the peripheral blood vessels with resulting lowering of the blood pressure. [2] [3] [4] Bezold-Jarisch reflex is responsible for 61% of bradyarrhythmia that occur within the first 60 minutes of inferoposterior myocardial infarction.[5] In addition, it is considered a good prognostic indicator of successful early reperfusion and coronary artery patency in the setting of thrombolysis after inferoposterior MI.
References
- ↑ Aviado DM, Guevara Aviado D (2001). "The Bezold-Jarisch reflex. A historical perspective of cardiopulmonary reflexes". Ann N Y Acad Sci. 940: 48–58. PMID 11458703.
- ↑ A. von Bezold, Ludwig Hirt (1844-1907): Über die physiologischen Wirkungen des essigsauren Veratrine. Untersuchungen aus dem Physiologischen Laboratorium in Würzburg, 1867, 1: 73-122.
- ↑ A. Jarisch, C. Henze Über Blutdrucksenkung durch chemische Erregung depressorischer Nerven. Naunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1937, 187: 706-730.
- ↑ A. Jarisch Vom Herzen ausgehende Kreislaufreflexe. Archiv für Kreislaufforschung 1940, 7: 260-274.
- ↑ Goldman, Lee; Anderson, Jeffrey L. "ST SEGMENT ELEVATION ACUTE MYOCARDIAL INFARCTION AND COMPLICATIONS OF MYOCARDIAL INFARCTION". Goldman: Goldman's Cecil Medicine (24th ed.). Saunders, an imprint of Elsevier Inc. p. 444. ISBN 978-1-4377-1604-7.