Familial combined hyperlipidemia: Difference between revisions
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==Overview== | ==Overview== | ||
The high [[VLDL]] levels are due to overproduction of substrates, including triglycerides, [[acetyl-CoA]], and an increase in B-100 synthesis. They may also be caused by the decreased | The high [[VLDL]] levels are due to overproduction of substrates, including triglycerides, [[acetyl-CoA]], and an increase in B-100 synthesis. They may also be caused by the decreased clea== Historical Perspective == | ||
==Historical perspective== | |||
*In 1967, Fredrickson using paper electrophosresis , classified lipoprotein disorder.<ref name="pmid32961932">{{cite journal| author=Culliton BJ| title=Fredrickson's bitter end at Hughes. | journal=Science | year= 1987 | volume= 236 | issue= 4807 | pages= 1417-8 | pmid=3296193 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3296193 }}</ref> | |||
==Classification== | |||
*There is no established classification for familial combined hyperlipidemia. | |||
==Pathophysiology== | |||
===Pathogenesis=== | |||
==Causes== | |||
The cause of type 1 hyperlipidemia remain | |||
==Differential diagnosis== | |||
==Epidemiology and Demographics== | |||
===Epidemiology=== | |||
===Demographics=== | |||
====Age==== | |||
====Gender==== | |||
==Screening== | |||
==Natural History, Complications, and Prognosis== | |||
===Natural History=== | |||
===Complications=== | |||
===Prognosis=== | |||
==Diagnosis== | |||
===History and symptoms=== | |||
Symptoms of | |||
===Physical examination=== | |||
*Signs of Type | |||
===Laboratory findings=== | |||
===Molecular Genetic Testing=== | |||
==Treatment== | |||
===Pregnancy Management=== | |||
===Investigative Therapies=== | |||
===Gene Therapy=== | |||
==Prevention== | |||
===Secondary prevention=== | |||
===Prevention of complications=== | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Lipopedia]] | |||
{{Lipopedia}} | |||
{{WikiDoc Help Menu}} | |||
{{WikiDoc Sources}} | |||
rance of [[LDL]]. Prevalence in the population is 10%. | |||
==References== | ==References== |
Revision as of 14:16, 14 November 2016
Lipoprotein Disorders Microchapters |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: Type IIB hyperlipoproteinemia
Overview
The high VLDL levels are due to overproduction of substrates, including triglycerides, acetyl-CoA, and an increase in B-100 synthesis. They may also be caused by the decreased clea== Historical Perspective ==
Historical perspective
- In 1967, Fredrickson using paper electrophosresis , classified lipoprotein disorder.[1]
Classification
- There is no established classification for familial combined hyperlipidemia.
Pathophysiology
Pathogenesis
Causes
The cause of type 1 hyperlipidemia remain
Differential diagnosis
Epidemiology and Demographics
Epidemiology
Demographics
Age
Gender
Screening
Natural History, Complications, and Prognosis
Natural History
Complications
Prognosis
Diagnosis
History and symptoms
Symptoms of
Physical examination
- Signs of Type
Laboratory findings
Molecular Genetic Testing
Treatment
Pregnancy Management
Investigative Therapies
Gene Therapy
Prevention
Secondary prevention
Prevention of complications
References
- ↑ Culliton BJ (1987). "Fredrickson's bitter end at Hughes". Science. 236 (4807): 1417–8. PMID 3296193.
Template:WikiDoc Sources rance of LDL. Prevalence in the population is 10%.