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Ochuko Ajari (talk | contribs) (Created page with "{{WBRQuestion |QuestionAuthor={{Ochuko}} |ExamType=USMLE Step 1 |MainCategory=Microbiology, Pathophysiology |SubCategory=General Principles, Infectious Disease |MainCategory=M...") |
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{{WBRQuestion | {{WBRQuestion | ||
|QuestionAuthor={{Ochuko}} | |QuestionAuthor={{Ochuko}} (Reviewed by {{YD}}) | ||
|ExamType=USMLE Step 1 | |ExamType=USMLE Step 1 | ||
|MainCategory=Microbiology, Pathophysiology | |MainCategory=Microbiology, Pathophysiology | ||
Line 8: | Line 8: | ||
|MainCategory=Microbiology, Pathophysiology | |MainCategory=Microbiology, Pathophysiology | ||
|SubCategory=General Principles, Infectious Disease | |SubCategory=General Principles, Infectious Disease | ||
|MainCategory=Microbiology, Pathophysiology | |||
|MainCategory=Microbiology, Pathophysiology | |MainCategory=Microbiology, Pathophysiology | ||
|MainCategory=Microbiology, Pathophysiology | |MainCategory=Microbiology, Pathophysiology | ||
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|MainCategory=Microbiology, Pathophysiology | |MainCategory=Microbiology, Pathophysiology | ||
|SubCategory=General Principles, Infectious Disease | |SubCategory=General Principles, Infectious Disease | ||
|Prompt=A 28-year old | |Prompt=A 28-year-old woman presents to the physician's office with complaints of fever, sore throat, and swelling in her axilla. Her temperature is 38.3 °C (101 °F), her blood pressure is 136/86 mmHg, and her heart rate is 100/min. Physical examination is remarkable for axillary lymphadenopathy. A throat swab is performed and sent for culture. Two days later, a gram-positive club-shaped rod that contains metachromatic granules forms black colonies on tellurite agar. What is the mechanism of virulence that characterizes the organism responsible for this patient's condition? | ||
|AnswerA=It binds to MHC II and T-cell receptor, resulting in polyclonal T-cell activation | |AnswerA=It binds to MHC II and T-cell receptor, resulting in polyclonal T-cell activation | ||
|AnswerB=It acts via antibodies to M proteins to enhance the host defenses | |AnswerB=It acts via antibodies to M proteins to enhance the host defenses | ||
|AnswerC=It inhibits protein synthesis via ADP ribosylation of EF-2 | |AnswerC=It inhibits protein synthesis via ADP ribosylation of EF-2 |
Revision as of 21:35, 2 January 2015
Author | [[PageAuthor::Ogheneochuko Ajari, MB.BS, MS [1] (Reviewed by Yazan Daaboul, M.D.)]] |
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Exam Type | ExamType::USMLE Step 1 |
Main Category | MainCategory::Microbiology, MainCategory::Pathophysiology |
Sub Category | SubCategory::General Principles, SubCategory::Infectious Disease |
Prompt | [[Prompt::A 28-year-old woman presents to the physician's office with complaints of fever, sore throat, and swelling in her axilla. Her temperature is 38.3 °C (101 °F), her blood pressure is 136/86 mmHg, and her heart rate is 100/min. Physical examination is remarkable for axillary lymphadenopathy. A throat swab is performed and sent for culture. Two days later, a gram-positive club-shaped rod that contains metachromatic granules forms black colonies on tellurite agar. What is the mechanism of virulence that characterizes the organism responsible for this patient's condition?]] |
Answer A | AnswerA::It binds to MHC II and T-cell receptor, resulting in polyclonal T-cell activation |
Answer A Explanation | AnswerAExp:: |
Answer B | AnswerB::It acts via antibodies to M proteins to enhance the host defenses |
Answer B Explanation | AnswerBExp:: |
Answer C | AnswerC::It inhibits protein synthesis via ADP ribosylation of EF-2 |
Answer C Explanation | AnswerCExp:: |
Answer D | AnswerD::It blocks GABA and glycine release from cells in the spinal cord |
Answer D Explanation | AnswerDExp:: |
Answer E | AnswerE::It produces catalase to degrade hydrogen peroxide |
Answer E Explanation | AnswerEExp:: |
Right Answer | RightAnswer::C |
Explanation | [[Explanation:: Educational Objective: |
Approved | Approved::Yes |
Keyword | |
Linked Question | Linked:: |
Order in Linked Questions | LinkedOrder:: |