High D-dimer causes: Difference between revisions
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==Overview== | ==Overview== | ||
Elevated levels of D-dimer signify the activation of hemostasis and fibrinolytic pathway. It is a non-specific marker that has been widely implicated in acute venous thromboembolism (VTE). However, D-dimer levels are also increased in patients with other conditions, such as cancer, pregnancy, infections, trauma, and recent surgery.<ref name="pmid18608117">{{cite journal| author=Lippi G, Franchini M, Targher G, Favaloro EJ| title=Help me, Doctor! My D-dimer is raised. | journal=Ann Med | year= 2008 | volume= 40 | issue= 8 | pages= 594-605 | pmid=18608117 | doi=10.1080/07853890802161015 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18608117 }} </ref> | |||
==Causes== | ==Causes== | ||
Revision as of 19:59, 25 September 2013
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High D-dimer causes On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Elevated levels of D-dimer signify the activation of hemostasis and fibrinolytic pathway. It is a non-specific marker that has been widely implicated in acute venous thromboembolism (VTE). However, D-dimer levels are also increased in patients with other conditions, such as cancer, pregnancy, infections, trauma, and recent surgery.[1]
Causes
- Age
- Aortic dissection
- Atherosclerosis
- Atrial fibrillation
- Heart failure
- Ischemic heart disease
- Liver disease
- Malignancy
- Pregnancy
- Primary pulmonary hypertension
- Renal disease
- Sickle cell disease
- Stroke
- Surgery
- Thromboembolism
- Trauma
References
- ↑ Lippi G, Franchini M, Targher G, Favaloro EJ (2008). "Help me, Doctor! My D-dimer is raised". Ann Med. 40 (8): 594–605. doi:10.1080/07853890802161015. PMID 18608117.