D-dimer prognostic role in thromboembolism occurrence: Difference between revisions
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==Overview== | ==Overview== | ||
== | ==Occurrence of VTE== | ||
* A study was conducted in China on 458 patients whose mean age is 77 years and who were hospitalized for at least 3 days for either heart failure, respiratory failure, ischemic stroke, infection or recent surgery in order to evaluate whether elevated D-dimer levels more than 500 ng/ml is associated with high risk of occurrence of [[VTE]] in elderly patients hospitalized for acute illness. [[VTE]] events were defined as either asymptomatic [[DVT]] diagnosed by compression [[ultrasound]] at the enrollment day and three weeks afterwards or symptomatic [[VTE]] within 90 days of the enrollement. The results of this study were adjusted for gender, age, [[BMI]], the acute medical disease and pre-existing comorbidities and they can be summarized as follow: | |||
** 49.1% of enrolled subjects had an elevated D-dimer level at the enrollment time, 14.2% of which developed [[VTE]] within the follow up period. | |||
** 5.6% of patients who had normal D-dimer developed [[VTE]]<ref name="pmid21463550">{{cite journal| author=Fan J, Li X, Cheng Y, Yao C, Zhong N, Investigators Group| title=Measurement of D-dimer as aid in risk evaluation of VTE in elderly patients hospitalized for acute illness: a prospective, multicenter study in China. | journal=Clin Invest Med | year= 2011 | volume= 34 | issue= 2 | pages= E96-104 | pmid=21463550 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21463550 }} </ref> | |||
==References== | ==References== | ||
Revision as of 14:31, 26 September 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]
Overview
Occurrence of VTE
- A study was conducted in China on 458 patients whose mean age is 77 years and who were hospitalized for at least 3 days for either heart failure, respiratory failure, ischemic stroke, infection or recent surgery in order to evaluate whether elevated D-dimer levels more than 500 ng/ml is associated with high risk of occurrence of VTE in elderly patients hospitalized for acute illness. VTE events were defined as either asymptomatic DVT diagnosed by compression ultrasound at the enrollment day and three weeks afterwards or symptomatic VTE within 90 days of the enrollement. The results of this study were adjusted for gender, age, BMI, the acute medical disease and pre-existing comorbidities and they can be summarized as follow:
References
- ↑ Fan J, Li X, Cheng Y, Yao C, Zhong N, Investigators Group (2011). "Measurement of D-dimer as aid in risk evaluation of VTE in elderly patients hospitalized for acute illness: a prospective, multicenter study in China". Clin Invest Med. 34 (2): E96–104. PMID 21463550.