IgA nephropathy overview: Difference between revisions
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==Overview== | ==Overview== | ||
IgA nephropathy (Berger’s disease) is considered the most common primary chronic glomerulonephritis. <ref name="pmid3329736">{{cite journal| author=D'Amico G| title=The commonest glomerulonephritis in the world: IgA nephropathy. | journal=Q J Med | year= 1987 | volume= 64 | issue= 245 | pages= 709-27 | pmid=3329736 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3329736 }} </ref> The clinical syndrome of IgA nephropathy is often unpredictable, although classically it is recognized as a nephritic syndrome with a presentation of recurrent painless gross hematuria following a respiratory or gastrointestinal tract infection in a young male patient. Nonetheless, asymptomatic IgA nephropathy with microscopic hematuria is not uncommon. | IgA nephropathy (Berger’s disease) is considered the most common primary chronic glomerulonephritis.<ref name="pmid3329736">{{cite journal| author=D'Amico G| title=The commonest glomerulonephritis in the world: IgA nephropathy. | journal=Q J Med | year= 1987 | volume= 64 | issue= 245 | pages= 709-27 | pmid=3329736 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3329736 }} </ref> The clinical syndrome of IgA nephropathy is often unpredictable, although classically it is recognized as a nephritic syndrome with a presentation of recurrent painless gross hematuria following a respiratory or gastrointestinal tract infection in a young male patient. Nonetheless, asymptomatic IgA nephropathy with microscopic hematuria is not uncommon.<ref name="pmid12213946">{{cite journal| author=Donadio JV, Grande JP| title=IgA nephropathy. | journal=N Engl J Med | year= 2002 | volume= 347 | issue= 10 | pages= 738-48 | pmid=12213946 | doi=10.1056/NEJMra020109 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12213946 }} </ref> Although not frequently performed, the definitive diagnosis to confirm the clinical suspicion of IgA nephropathy is kidney biopsy that not only carries diagnostic benefit, but also has prognostic implications. | ||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
IgA nephropathy (Berger’s disease) is considered the most common primary chronic glomerulonephritis.[1] The clinical syndrome of IgA nephropathy is often unpredictable, although classically it is recognized as a nephritic syndrome with a presentation of recurrent painless gross hematuria following a respiratory or gastrointestinal tract infection in a young male patient. Nonetheless, asymptomatic IgA nephropathy with microscopic hematuria is not uncommon.[2] Although not frequently performed, the definitive diagnosis to confirm the clinical suspicion of IgA nephropathy is kidney biopsy that not only carries diagnostic benefit, but also has prognostic implications.
References
- ↑ D'Amico G (1987). "The commonest glomerulonephritis in the world: IgA nephropathy". Q J Med. 64 (245): 709–27. PMID 3329736.
- ↑ Donadio JV, Grande JP (2002). "IgA nephropathy". N Engl J Med. 347 (10): 738–48. doi:10.1056/NEJMra020109. PMID 12213946.