IgA nephropathy causes: Difference between revisions
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<u>The most important 3 causes are:</u> | <u>The most important 3 causes are:</u> | ||
* '''Liver cirrhosis'''<ref name="pmid22895519">{{cite journal| author=Radhakrishnan J, Cattran DC| title=The KDIGO practice guideline on glomerulonephritis: reading between the (guide)lines--application to the individual patient. | journal=Kidney Int | year= 2012 |volume= 82 | issue= 8 | pages= 840-56 | pmid=22895519 | doi=10.1038/ki.2012.280 | pmc=|url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22895519 }} </ref> | * '''Liver cirrhosis'''<ref name="pmid22895519">{{cite journal| author=Radhakrishnan J, Cattran DC| title=The KDIGO practice guideline on glomerulonephritis: reading between the (guide)lines--application to the individual patient. | journal=Kidney Int | year= 2012 |volume= 82 | issue= 8 | pages= 840-56 | pmid=22895519 | doi=10.1038/ki.2012.280 | pmc=|url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22895519 }} </ref> | ||
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* '''HIV infection'''<ref name="pmid22895519">{{cite journal| author=Radhakrishnan J, Cattran DC| title=The KDIGO practice guideline on glomerulonephritis: reading between the (guide)lines--application to the individual patient. | journal=Kidney Int | year= 2012 |volume= 82 | issue= 8 | pages= 840-56 | pmid=22895519 | doi=10.1038/ki.2012.280 | pmc=|url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22895519 }} </ref> | * '''HIV infection'''<ref name="pmid22895519">{{cite journal| author=Radhakrishnan J, Cattran DC| title=The KDIGO practice guideline on glomerulonephritis: reading between the (guide)lines--application to the individual patient. | journal=Kidney Int | year= 2012 |volume= 82 | issue= 8 | pages= 840-56 | pmid=22895519 | doi=10.1038/ki.2012.280 | pmc=|url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22895519 }} </ref> | ||
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Revision as of 21:37, 21 October 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Causes
Primary IgA Nephropathy
Primary IgA nephropathy is caused by a genetic predisposition in patients who typically present immediately following a respiratory or gastrointestinal tract infectious organisms or virus. The environmental exposure to these infectious agents may thus facilitate the subsequent pathogenesis of the disease.
Secondary IgA Nephropathy
Common primary etiologies associated with glomerular IgA deposits and thus secondary IgA nephropathy are shown below.
The most important 3 causes are:
- Liver cirrhosis[1]
- Celiac disease[1]
- HIV infection[1]
IgA nephropathy has also been associated with the following diseases, but to a much less extent:
- Dermatitis herpetiformis[1]
- Seronegative arthritis, especially as ankylosing spondylitis[1]
- Small-cell carcinoma[1]
- Hodgkin’s lymphoma[1]
- T-cell lymphoma, such as mycosis fungoides[1]
- Disseminated tuberculosis[1]
- Bronchiolitis obliterans[1]
- Inflammatory bowel disease (Crohn’s disease and ulcerative colitis)[1]