Polycystic kidney disease history and symptoms: Difference between revisions
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{{Polycystic kidney disease}} | {{Polycystic kidney disease}} | ||
{{CMG}} {{AE}} | {{CMG}} {{AE}} [[User:Sergekorjian|Serge Korjian]],[[User:YazanDaaboul|Yazan Daaboul]] | ||
==Overview== | ==Overview== | ||
Revision as of 04:25, 17 November 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Serge Korjian,Yazan Daaboul
Overview
Common clues for ADPKD on history include flank or back pain, nocturia and polyuria, headache and family history of renal failure or diagnosed renal cystic diseases.
History
Early ADPKD is asymptomatic and clinical diagnosis is usually with family history and imaging. Common symptoms at presentation include:[1][2]
- Flank/Back pain due to an enlarging cyst, cyst infection or hemorrhage, nephrolithiasis, and pyelonephritis.
- Headache due to hypertension
- Polyuria and nocturia due to loss of concentrating ability
- Hematuria
- Dyspnea, early satiety, and obstructive jaundice due to enlarging hepatic cysts
Other important clues on history include:
- Detailed family history of renal failure and cystic diseases
- Detailed family history of intracranial aneurysms and aneurysmal rupture to assess patient risk
References
- ↑ Gabow PA (1993). "Autosomal dominant polycystic kidney disease". N Engl J Med. 329 (5): 332–42. doi:10.1056/NEJM199307293290508. PMID 8321262.
- ↑ Torres VE, Harris PC, Pirson Y (2007). "Autosomal dominant polycystic kidney disease". Lancet. 369 (9569): 1287–301. doi:10.1016/S0140-6736(07)60601-1. PMID 17434405.