Nephrotic syndrome laboratory findings: Difference between revisions

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Revision as of 08:49, 17 November 2013

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

For the diagnosis of nephrotic syndrome^[1]:

When nephrotic syndrome is diagnosed (proteinuria > 3.5 g/24 hrs), the following laboratory evaluation is needed^[1]:

Low serum albumin levels
Serum chemistry panel is generally normal. Pseudohyponatremia due to hyperlipidemia may be present.
Abnormal lipid panel
Normal/elevated plasma creatinine levels

Other tests may be necessary to rule-out secondary etiologies of nephrotic syndrome^[1]:

@@ Line 26: / Line 26: @@
 *VDRL or RPR
 *Serum and urine protein electrophoresis
-==Renal Biopsy==
-Renal biopsy is usually recommende for patients with nephrotic syndrome. Renal biopsy provides diagnostic and prognostic benefit. However, guidelines that define the timing and the circumstances to perform renal biopsy are not present. In minimal change disease, the most common primary cause of nephrotic syndrome in children, and in diabetic nephropathy, the most common secondary cause of nephrotic syndrome in adults, renal biopsy is not generally recommended and is not routinely performed.<ref name="pmid19904897">{{cite journal| author=Kodner C| title=Nephrotic syndrome in adults: diagnosis and management. | journal=Am Fam Physician | year= 2009 | volume= 80 | issue= 10 | pages= 1129-34 | pmid=19904897 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19904897 }} </ref>
 ==References==